Invasive pneumococcal disease and carriage among children with sickle cell disease in ghana: a post-vaccination study

Active Project Grant Awarded Last action

Award ID
R01AI169674
Recipient
Awarding agency
Obligated
$694,614

Award facts

Assistance listing
93.855 Allergy and Infectious Diseases Research
Completion date 90% complete
Place of performance
Ghana

Award details come from USAspending.gov.

Description

Abstract
Pneumococcal carriage is the precursor for development of pneumococcal disease, and is also responsible for transmission of the organism from person-to-person. Children with sickle cell disease (SCD) are particularly susceptible to invasive pneumococcal disease (IPD) due to the i n a b i l i t y of their defective immune system to effectively handle encapsulated bacteria. This has led to the recommendation of anti-pneumococcal prophylaxis for SCD children including the administration of penicillin and the 23-valent polysaccharide vaccine (PPV23) in the past. Though these prophylactic measures decreased the rate of IPD among SCD children, breakthrough disease still occurred, mostly in children aged

Transactions

Action Obligated Date
Amendment $99,598
Amendment $123,489
Amendment $105,754
Amendment $105,754
Amendment $125,095
Amendment $0
Amendment $0
Amendment $0
Original award $134,924

Quick answers

Who received award R01AI169674?

R01AI169674 was awarded to University Of Ghana by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on May 12, 2022.

How much is award R01AI169674 worth?

$694,614 has been obligated on R01AI169674.

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