Project Grant R01AG097491
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded The Leland Stanford Junior University a project grant of $1,176,501 on March 15, 2025, under the Aging Research program (CFDA 93.866) to develop innovative research tools and datasets for understanding Alzheimer's disease etiology. The primary deliverables include COMBO-SEQ/TAG, a comprehensive toolkit that combines precise installation of multiple risk alleles (COMBO-SEQ) with a multiplex protein tagging tool...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded The Leland Stanford Junior University a $620,020 project grant effective September 30, 2025, through August 31, 2027, under the Aging Research program (CFDA 93.866). This research project will develop and analyze a novel individual-level database linking health trajectories of older adults to the physical, mental, and economic well-being of their family members across multiple generations, covering a 25-year period...
- Federal Project Grant Award Summary The Leland Stanford Junior University received a $2.2 million project grant from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), awarded on September 30, 2025, with a completion date of July 31, 2030. This grant funds fundamental research investigating how the peripheral nervous system coordinates organ function during aging and whether targeted interventions can restore organ...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded $770,000 to The Leland Stanford Junior University under the Aging Research program (CFDA 93.866) on August 15, 2025, for a basic science research project addressing postoperative delirium in geriatric populations. The project, titled "Targeting Aging-Related Delays in Cognitive Recovery After Anesthesia by Attenuating Oxidative Stress: Implications for Alzheimer's Disease," will investigate the role of...
- Federal Grant Award Summary The National Institute on Aging awarded The Leland Stanford Junior University a $762,636 Project Grant effective May 15, 2025, through March 31, 2030, under the Aging Research program (CFDA 93.866). This award supports the development of interpretable machine learning (ML) and explainable artificial intelligence (XAI) methods to identify causal genetic variants associated with Alzheimer's disease (AD). The research addresses a critical gap in current genome-wide...
- Federal Project Grant Award Summary The Leland Stanford Junior University received a $1,526,066 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded June 1, 2025, with an ultimate completion date of April 30, 2030. This research project investigates shared mechanisms of tau toxicity across neurodegenerative diseases, with particular focus on understanding the mechanistic connection between tau abnormality and mitochondrial...
- This Project Grant award of $423,500.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research at The Leland Stanford Junior University (Stanford University) to study behavioral, electrophysiological, and pupil-based rhythms of attention and memory in young and older adults. The project aims to examine how feature-based attention and episodic memory performance vary with age, independent of Alzheimer's disease, by conducting a well-powered study with simultaneous...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded a Project Grant of $433,125 to the University of California, Los Angeles (UCLA), effective August 1, 2025, through July 31, 2027, under the Aging Research program (CFDA 93.866). This award funds a two-year research project investigating the molecular and cellular characteristics of striatal astrocytes during the aging process. The research aims to elucidate how astrocytes—a critical glial cell type involved in...
- Federal Grant Award Summary The National Institute on Aging awarded a $2.22 million Project Grant to the University of California, Irvine under the Aging Research program (CFDA 93.866) for the period September 1, 2025 through August 31, 2027. This award supports the development and optimization of enhancer adeno-associated virus (AAV) vectors—genetically engineered viral tools designed to provide cell-type-specific genetic access and manipulation capabilities in the brain. The primary...
- Federal Grant Award Summary Award Overview: The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded J. David Gladstone Institutes a Project Grant of $817,357 (awarded June 15, 2025; completion date March 31, 2030) to advance machine learning approaches for behavioral analysis in Alzheimer's disease research. The grant funds development and validation of the Variational Animal Motion Embedding (VAME) platform, an advanced machine learning system designed...
The National Institute on Aging (NIA) awarded The Leland Stanford Junior University a $1,468,868 Project Grant on January 15, 2026, under the Aging Research program (CFDA 93.866) to support a multi-investigator research initiative examining the brain's role as a neural pacemaker in regulating organismal aging. The research will be conducted through November 30, 2030, at Stanford's California campus. This initiative leverages the killifish model organism—a vertebrate with a naturally compressed lifespan of approximately six months—to conduct high-throughput, longitudinal studies of aging and longevity. The project integrates advanced methodologies including artificial intelligence-enabled video-tracking analysis, genetic screening, multi-omics datasets, and novel tools for interrogating neural systems throughout the lifespan to identify central drivers of aging and develop evidence-based interventions. The deliverables under this award encompass original research findings and technological innovations in systems-level aging biology, including behavioral biomarkers predictive of aging trajectories, identification of novel neuropeptides affecting lifespan, molecular phenotype characterization in response to longevity interventions, and unbiased maps of neural control centers governing aging processes. This research directly supports the NIA's mission to advance understanding of the aging process and age-related diseases through rigorous biomedical investigation, with potential implications for preventing and treating conditions affecting older populations.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.5m | 1/8/26 |