Project Grant R01AG096914
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Utah $437,252 under the Aging Research program (CFDA 93.866) for the period January 1, 2026, through December 31, 2030. This project grant supports the development and validation of a plasma biomarker for TDP-43 (TAR DNA-binding protein of 43 kDa) proteinopathy across Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). The research team will investigate a novel monoclonal...
- Federal Grant Award Summary The University of Utah received a $847,000 Project Grant from the National Institute on Aging (CFDA 93.866 – Aging Research program) awarded April 15, 2026, with a completion date of March 31, 2028. This project addresses decision-making capacity assessment and inclusive decision-making approaches for older persons with decisional impairments, particularly those with Alzheimer's disease and related dementias. The research focuses on examining how capacity...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded $429,000 to the University of Colorado-Denver under the Aging Research program (CFDA 93.866) for a two-year project period commencing May 1, 2026 and concluding April 30, 2028. This R21 exploratory/developmental grant funds research investigating lysosome-Golgi membrane contact sites (LG-MCS) as regulators of senescence-associated inflammation. The project aims to define the molecular architecture and functional...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded J. David Gladstone Institutes a Project Grant of $1,459,072 on August 1, 2025, under the Aging Research program (CFDA 93.866) to conduct research on Alzheimer's Disease (AD)-related neurological dysfunction. The research will deliver scientific knowledge and methodological innovations focused on understanding how inhibitory interneurons—specifically parvalbumin (PVALB) and somatostatin (SST) cell types—contribute...
- Federal Project Grant Award Summary The University of Texas at Austin received a $438,625 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) effective September 1, 2025, through August 31, 2027. The award funds research investigating the heterogeneity of interneuron vulnerability in aging and Alzheimer's disease using advanced ultraplex correlative light and electron microscopy (CLEM) techniques. The research aims to decode why certain...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded a Project Grant of $442,485 to the University of Colorado-Denver for the period of June 1, 2026 through May 31, 2028 under the Aging Research program (CFDA 93.866). This award supports research investigating the selective vulnerability of the locus coeruleus and hypothalamus to herpes simplex virus type 1 (HSV-1) infection in Alzheimer's disease progression. The project deliverables include advanced spatial transcriptomics...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of South Florida $3.297 million under the Aging Research program (CFDA 93.866) for a four-year project period (September 1, 2025 – August 31, 2029) to develop novel peptidomimetic biomaterials that inhibit amyloid-beta (Aβ42) aggregation in Alzheimer's disease. The research deliverables include the rational design and characterization of structurally related analogues to a lead compound that stabilizes Aβ...
- Federal Project Grant Award Summary The University of California, San Diego received a $3.14 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded September 15, 2025, with completion targeted for August 31, 2029. This research initiative will deliver comprehensive scientific analysis of human brain neuropeptidomes and their biosynthetic proteases in normal aging and Alzheimer's disease (AD) conditions. The project will elucidate the...
- Federal Project Grant Award Summary The University of Miami's Office of Research Administration received a $109,652.00 project grant from the National Institute on Aging under the Aging Research program (CFDA 93.866), awarded September 5, 2026, with a completion date of September 4, 2027. This grant supports research into T cell senescence-driven immune dysfunction in aging and HIV-positive populations. The project will deliver scientific research products including a comprehensive T cell...
- Federal Grant Award Summary The University of Michigan, through its Office of Research and Sponsored Projects, received a $284,108 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) for the period January 1, 2026 through December 31, 2027. This research initiative, conducted at the Ann Arbor campus, focuses on elucidating how mechanical changes in the aging brain—specifically alterations in tissue stiffness and viscoelasticity—influence microglial...
The University of Utah's Office of Sponsored Projects received a $612,346 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective June 1, 2026, through February 28, 2031. This collaborative research initiative investigates age-associated decline of meningeal gamma-delta T (GDT) cells and their modulation through the gut-meninges axis. The project will generate fundamental scientific discoveries regarding how aging influences meningeal GDT cells, the regulatory mechanisms by which gut microbes control these immune cells, and gut-centric interventions capable of driving GDT cell rebound in advanced age. The primary deliverable is basic and translational research directed toward understanding how to fortify GD17 cells to support brain health and cognitive function in aging populations. The research addresses a critical gap in aging science by identifying and characterizing brain-regulatory factors amenable to intervention in advanced age, with potential applications for preventing or mitigating age-related cognitive decline. This project aligns with the NIA's mission to support biomedical and behavioral research toward understanding the aging process and age-related diseases, with particular emphasis on neurodegenerative disease prevention and treatment mechanisms.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $612.3k | 6/1/26 |