The National Institute on Aging (NIA) awarded a $614,424 Project Grant (CFDA 93.866 - Aging Research) to the University of Washington to conduct research on Alzheimer's disease (AD) pathogenesis. The research aims to use novel explainable AI techniques and induced pluripotent stem cell (iPSC) models to better understand the role of microglia, the brain's immune cells, in the early stages of AD development. The project will integrate the AI approach with deep learning methods to identify subtle...
The National Institute on Aging (NIA) awarded a $661,016 Project Grant (CFDA 93.866 - Aging Research) to the University of Southern California (USC) to develop a "Federated Deep Learning to Accelerate Alzheimer's Disease Research" platform. This project aims to leverage innovative artificial intelligence (AI) techniques and distributed computing to analyze Alzheimer's disease (AD) biobanks from the U.S., India, Japan, and Europe, totaling over 100,000 MRI and PET scans. The key...
This federal Project Grant award, provided by the National Institute on Aging under CFDA 93.866 Aging Research, aims to develop explainable and ethical artificial intelligence (AI) models to assist in the diagnosis and prognosis of Alzheimer's disease (AD). The $738,014 award to Emory University, with a period of performance from August 1, 2024 to April 30, 2029, will leverage the institution's expertise in explainable AI, cerebrospinal fluid proteomics, and understanding the role of factors...
The National Institute on Aging (NIA), part of the Department of Health and Human Services National Institutes of Health, awarded a $3.37 million Project Grant to The University of Texas at Arlington to develop an individualized deep connectome framework for Alzheimer's disease and related dementias (ADRD) analysis. The three-year grant, awarded on August 18, 2022 under the NIA's Aging Research program (CFDA 93.866), will support research to discover and identify individualized...
This $155,000 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research at Wake Forest University Health Sciences (WFUHS) to identify potential microRNA (miRNA) biomarkers for early detection and progression of Alzheimer's disease (AD). The key objectives are to: Discover circulating miRNA biomarkers that can distinguish between individuals at different stages of AD, including those with mild cognitive impairment. This could enable earlier...
This $287,118 Project Grant was awarded on September 1, 2023 by the National Institute on Aging (NIA) under the Aging Research (CFDA 93.866) grant program. The grant will fund the development of techniques to use deep transfer learning and multimodal data, including brain MRIs, genetic information, and cognitive tests, to enable the early detection and forecasting of Alzheimer's disease progression. The University of Massachusetts (UMass), as the prime awardee, will create an end-to-end...
The National Institute on Aging (NIA) awarded a $762,636 Project Grant under the Aging Research Federal Grant Program (CFDA 93.866) to The Leland Stanford Junior University (Stanford University) to develop rigorous machine learning (ML) methods and pair them with causal inference to discover causal genetic variants associated with Alzheimer's disease (AD). The project aims to significantly improve the understanding of the multiplex nature of AD and provide a credible set of well-defined, novel...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to The Research Foundation For The State University Of New York, doing business as Upstate Medical Center, provides $107,948.00 to enhance the understanding of biological signatures that distinguish subtypes of Alzheimer's disease (AD). The goal is to use state-of-the-art computational approaches to jointly analyze genetic, epigenetic, and neuroimaging data to identify AD subtypes that can be...
The National Institute on Aging (NIA) awarded a Project Grant under the Aging Research federal grant program (CFDA 93.866) to the University of Wyoming to integrate experimental and computational models to study prefrontal microcircuit changes during aging and Alzheimer's disease. The $174,242 award, which runs from September 1, 2024 to June 30, 2026, will leverage in vivo calcium imaging, computational simulation modeling, and neural decoding to better understand how normal aging and...
This federal Project Grant award, valued at $6,226,692.00 and funded by the National Institute on Aging (CFDA 93.866 - Aging Research), supports research to investigate the role of neuronal hyperexcitability and proteostasis in the progression of Alzheimer's disease (AD). The study aims to track early electrophysiological changes in the locus coeruleus (LC) and hippocampus (HPC) as key brain regions impacted by the accumulation of beta-amyloid and tau proteins. The research seeks to understand...