Project Grant R01AG090379
- The National Institute on Aging (NIA), through its Aging Research federal grant program (CFDA 93.866), awarded a $636,342 Project Grant to Trustees of Boston University (doing business as Boston University Medical Campus) to conduct research on normal and pathological brain aging. The grant, with a performance period from August 1, 2025 to April 30, 2030, will support a multiscale modeling and empirical study of progressive myelin dystrophy, loss of synapses, and neuronal hyperexcitability in...
- This federal Project Grant award of $423,500 from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research into the behavioral, electrophysiological, and pupil-based rhythms of attention and memory in young and older adults. The project will examine attention and memory performance concurrently with electroencephalography (EEG) and pupillometry, with a sample of 75 young and 75 cognitively unimpaired older adults screened for Alzheimer's disease pathology. The goal is...
- This federal Project Grant award of $698,032 from the National Institutes of Health (NIH) National Institute on Aging (CFDA 93.866 Aging Research) is focused on testing the mechanisms that link high-level cognition and perception in normal aging. The research project, conducted by the University of Texas at San Antonio, aims to determine if attention control and effort, which decline with age, are the common mechanisms that connect perception and cognition. The study will use a multimodal...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) to the Trustees of Boston University, doing business as Boston University Medical Campus, provides $2,330,859.00 in funding to study age-related changes in brain network connectivity and their relationship to cognitive decline. The 3-year project aims to use multimodal neuroimaging, single-cell transcriptomics, electrophysiology, and neural tract-tracing in a rhesus monkey model to delineate how...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) is providing $231,276 to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania, to conduct a research project investigating the neurocognitive mechanisms underlying age-related declines in episodic memory representational specificity. The key objectives of the project are to: (1) identify EEG correlates of variations in episodic...
- This federal Project Grant award of $441,612 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Trustees of Boston University (Boston University Medical Campus) supports research to evaluate the use of digital cognitive measures, such as digital pen tasks and voice recordings, to monitor early cognitive decline in relation to modifiable Alzheimer's disease risk factors. The project aims to leverage the Framingham Heart Study's longitudinal data on digital cognitive...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $705,385 to Northeastern University to conduct a large-scale study investigating mediators and moderators of executive function training in older adults. The study aims to improve the rigor and reproducibility of research on cognitive plasticity in older adults, many of whom are at risk for Alzheimer's disease and related dementias. The study will collect data from 1,250 older adults aged 60+ to...
- This federal Project Grant award of $2,631,670 from the National Institute on Aging (CFDA 93.866 Aging Research) supports a research initiative at The Washington University to investigate age-related deficits in episodic memory. The project aims to determine how aging distinctly affects the content and structure of memory representations, and how this relates to dysfunction in different brain networks based on susceptibility to Alzheimer's disease pathology. The research will utilize plasma...
- This $749,108 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to understand how memory failures lead to decision failures across the lifespan. The research will use computational and neurobiological approaches to measure the influence of different types of memory - item, context, and statistical learning - on decision-making choices. The project will examine these questions in cognitively normal older adults through behavioral tasks,...
- The National Institutes of Health's National Institute on Aging awarded $256,331.40 under the Aging Research program (CFDA 93.866) to The Trustees of the University of Pennsylvania from February to October 2021. The project aims to develop novel machine learning algorithms and biomedical software to more accurately quantify brain aging and predict the onset of neurodegenerative diseases such as Alzheimer's. Specifically, the funding will support refining predictive models of the...
This Project Grant award of $343,350, provided by the National Institute on Aging (NIA, CFDA 93.866 Aging Research), supports research to investigate the neurocomputational mechanisms underlying age-related deficits in visual perception. The project aims to examine the role of alpha-gamma neural oscillations in deteriorating contrast sensitivity and 3D structure-from-motion perception, which significantly impact the health and quality of life of aging adults. Employing functional and structural MRI, high-density EEG, and source reconstruction techniques, the research will analyze how the dynamic phase structure of these interacting low- and high-frequency brain oscillations contributes to visual perception impairments across the adult lifespan, with a focus on Alzheimer's disease. This 5-year project, scheduled to run from September 2025 to August 2030, is being conducted by the Trustees of Boston University, a private research university with extensive expertise in aging research and neuroscience.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $343.4k | 9/12/25 |