This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to validate the use of ultrasound imaging as a bedside tool for characterizing swallowing biomechanics and enabling biofeedback therapy for individuals with swallowing disorders (dysphagia). The $432,534 award to the University of Cincinnati will: 1) Compare ultrasound measurements of oropharyngeal movements to gold-standard videofluoroscopic swallowing studies, and evaluate how these relate...
This National Science Foundation project grant of $390,000 will fund the development of a multihaptic wearable sensor enabled by a biomimetic polymer to support swallowing rehabilitation therapy. Awarded October 1, 2022 through the Engineering directorate (CFDA 47.041), the three-year grant provides funding to the University of California, San Diego to design an epidermal patch containing strain gauges, electromyography electrodes, and haptic stimulation capabilities. The patch will measure...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $852,049 to The Feinstein Institutes for Medical Research to conduct a prospective observational study on oropharyngeal dysphagia (OD) improvement in hospitalized patients with Alzheimer's disease and related dementias (AD/ADRD). The key objectives are to: 1) Develop and silently validate a machine learning model to predict which AD/ADRD patients are likely to experience clinical OD...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $423,788 to The Medical University of South Carolina to conduct research on brain networks supporting oral and pharyngeal swallow function after stroke. The key products and services to be delivered under this grant include: Identifying and assessing the brain networks and...
This $731,994 federal Project Grant award, provided by the U.S. Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (CFDA 10.310), is focused on developing thickened fluids fortified with added proteins for patients with dysphagia (swallowing difficulties). The key objectives are to (1) carefully select hydrolyzed proteins and thickening agents that can be effectively combined to create protein-fortified thickened fluids,...
The U.S. Food and Drug Administration (FDA) awarded a $249,999 Cooperative Agreement under the FDA Research program (CFDA 93.103) to Sibel Health Inc. The project aims to develop and validate the ADAM sensor, a novel wireless device designed to continuously monitor swallowing and respiratory patterns in Parkinson's disease patients with dysphagia. The comprehensive validation efforts will involve technical verifications, software testing, and clinical studies at Northwestern University to refine...
This Project Grant award of $435,915 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research program supports research at Northwestern University to advance the understanding of esophageal diseases and swallowing disorders. The key objectives are to develop new assessment approaches that combine measurements of esophageal neuromuscular function and wall biomechanics to better diagnose and...
This federal Project Grant award of $1,901,570.00 from the National Institute on Aging's Aging Research program (CFDA 93.866) supports the development and evaluation of the MIGO TRACKER, a wearable exercise monitoring system for remote therapeutic monitoring (RTM) of home exercise adherence in individuals recovering from stroke. The primary objectives are to: 1) complete firmware development for the MIGO TRACKER based on end-user feedback; 2) develop an online HIPAA-compliant RTM dashboard for...
This $390,823 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research to identify treatment-resistant components of feeding and their neuropathological correlates in Parkinson's disease (PD). The central hypothesis is that specific components of the feeding process are differentially impaired by neurodegeneration inside and outside the substantia nigra, resulting in an overall...
The National Institute on Aging awarded a Project Grant (CFDA 93.866 - Aging Research) totaling $257,983 to the University of Colorado-Denver to conduct a multi-center randomized trial investigating the use of corticosteroids to improve post-extubation swallowing function and reduce aspiration in acute respiratory failure survivors. The grant will fund a study to evaluate whether a short course of intravenous corticosteroids can reduce laryngeal edema and improve swallowing outcomes in this...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to determine the efficacy of surface electromyography (sEMG) biofeedback as an adjunct to in-person and telehealth swallowing therapy for patients with chronic stroke or Parkinson's disease and dysphagia (oropharyngeal swallowing disorders). The $549,106 award will fund a large-scale randomized clinical trial to compare the safety, satisfaction, and efficacy of sEMG biofeedback-facilitated swallow therapy delivered in-person versus remotely to a standard-of-care approach. The long-term goal is to improve neurogenic dysphagia management by developing evidence-based and accessible treatments. The award was granted to Purdue University, a prominent research institution with extensive experience executing federal grants and contracts across multiple domains.