Project Grant R01AA033112
- Federal Project Grant Award Summary Drexel University received a $564,306 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded May 1, 2026, with completion targeted for January 31, 2031. The project investigates the suppression of ethanol dependence-induced maladaptive appetitive and consummatory behavior through glucagon-like peptide-1 (GLP-1) system activation. Specifically, the research will examine how...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Pennsylvania $727,664 under the Alcohol Research Programs (CFDA 93.273) to conduct multi-omics spatial analysis of single mouse brain neurons and astrocytes in response to ethanol challenge. The five-year project, spanning May 1, 2026 through February 28, 2031, delivers research services focused on understanding the genomic and molecular consequences of alcohol abuse in...
- Federal Grant Award Summary Wake Forest University Health Sciences received a $2.55 million Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), awarded September 5, 2025, with completion targeted for August 31, 2029. The grant supports research investigating the insula-bed nucleus of the stria terminalis (BNST) neural circuit's role in regulating alcohol use disorder (AUD). The research project focuses on...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded $613,750 to The Regents of the University of California, San Francisco on June 15, 2026, under the Alcohol Research Programs (CFDA 93.273) to fund research investigating the relationship between brain glucose metabolism and alcohol use disorder (AUD). The project, scheduled for completion by April 30, 2031, focuses on elucidating molecular mechanisms by which alcohol alters glycolysis—the...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of Pennsylvania a Project Grant of $115,307 under the Alcohol Research Programs (CFDA 93.273) for the period September 1, 2025, through August 31, 2027. This K99/R00 career development award supports research examining the neuropharmacological effects of the ketogenic diet (KD) on alcohol intoxication in both healthy individuals and those with alcohol use disorder (AUD). The research...
- Federal Project Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Texas A&M University System Health Science Center a $635,002 Project Grant on June 15, 2026 (with completion scheduled for April 30, 2031) under the Alcohol Research Programs (CFDA 93.273) to conduct basic neuroscience research on cholinergic modulation of striatal circuits in alcohol use disorder (AUD). The research will investigate how chronic alcohol intake affects acetylcholine...
- Federal Grant Award Summary The Medical University of South Carolina received a $919,414 Project Grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) awarded September 5, 2025, with a completion date of May 31, 2030. The project, titled "OFC Astrocytes and Ethanol," investigates the neurobiological mechanisms underlying alcohol use disorder (AUD) by examining how chronic intermittent ethanol exposure affects...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $413,496 Project Grant to The Research Foundation for the State University of New York on September 20, 2025, to support research under the Alcohol Research Programs (CFDA 93.273). The project, titled "Enhancing Alcohol Use Disorder Recovery by Capturing the Dynamics of Psychological Well-Being in Daily Life," will operate through August 31, 2027, and will be conducted at the...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded the University of New Mexico Health Sciences Center a Project Grant of $160,744 effective March 9, 2026, with completion targeted for December 31, 2030, under the Alcohol Research Programs (CFDA 93.273) funding mechanism. The award supports biomedical research investigating the neurophysiological mechanisms underlying cognitive control deficits associated with prenatal alcohol exposure (PAE) and...
- Federal Grant Award Summary The National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) awarded $561,966 to the University of Arkansas for Medical Sciences on May 1, 2026, with a completion date of January 31, 2031. This Project Grant funds research to define the mechanisms by which ethanol exposure causes pathology in the developing central nervous system with the objective of generating therapeutics to prevent and treat Fetal Alcohol...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded Drexel University a Project Grant totaling $450,372 (awarded July 15, 2026, with completion targeted for March 31, 2031) under the Alcohol Research Programs (CFDA 93.273) to conduct research on ethanol-induced dysregulation of the astrocyte glucocorticoid system. The project investigates the relationship between alcohol use disorder (AUD), depression, and anxiety disorders—particularly in women—by examining how chronic ethanol exposure disrupts glucocorticoid signaling and astrocyte function in the brain. Specifically, the research employs a chronic intermittent ethanol vapor inhalation mouse model to characterize how ethanol perturbs the astrocyte glucocorticoid receptor system in the nucleus accumbens and impacts stress responsivity and reward-seeking behavior, with preliminary work suggesting that chemogenetic activation of astrocytic signaling may restore resilience in ethanol-exposed female mice. This biomedical research project contributes to NIAAA's mission to develop fundamental knowledge applicable to improved treatment methods and prevention strategies for alcoholism and alcohol-related disorders. The work addresses the comorbidity of AUD with mood and anxiety disorders and aims to elucidate mechanistic pathways involving the chaperone protein FKBP51 and glucocorticoid receptor regulation that may inform future pharmacological interventions and sex-specific treatment approaches for individuals with co-occurring substance use and mental health conditions.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $450.4k | 7/17/26 |