Project Grant R01AA031656
- This Project Grant award, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program, is funding a $167,500 research study titled "An Investigation of Sex Differences in Excessive Alcohol Use in Young Adulthood and Middle Age: Characterizing the Influence of Multiple Social Roles, Stress, and Poor Mental Health." The study, conducted by the University of Massachusetts Medical School, aims to examine...
- This Project Grant award, totaling $560,108.00 and spanning September 15, 2025 to August 31, 2030, was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The purpose of the project is to investigate the neurocognitive mechanisms that promote resilience to alcohol use disorder (AUD) in individuals with a family history of AUD. Specifically, the research will examine how attentional abilities may...
- This federal Project Grant award of $152,643 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), supports the development and characterization of a novel positron emission tomography (PET) radioligand, (S)-[18F]OF-NB1, to quantify the availability of GluN2B-containing N-methyl-D-aspartate receptors (GluN2BR) in people with alcohol use disorder (AUD). The two-phase project will first establish the imaging properties and...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a 5-year, $597,000 Project Grant titled "Sex-Dependent Shifts in Behavioral Profiles and Cortical Signaling Following Adolescent Binge Drinking" to The Pennsylvania State University. The grant, funded under CFDA 93.273 Alcohol Research Programs, aims to characterize changes in behavior, cortical adaptations in somatostatin neuron function and peptide signaling, and functional connectivity following adolescent...
- This federal Project Grant award of $2,552,568.00, awarded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) program, supports research to investigate the relationship between stress-induced neuroadaptations in the insula-BNST pathway and subsequent alcohol use disorder (AUD)-related behavior. The project, conducted by Wake Forest University Health Sciences, aims to elucidate how stress activation of AUD-associated...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $498,002 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Illinois to conduct a study aimed at increasing alcohol abstinence in young adults with alcohol use disorder (AUD). The overall goals of this 3-year project are to: (1) test the efficacy of combining contingency management (CM) with problem-solving therapy (CM-PST) versus CM alone in a 2-arm pilot randomized controlled trial, and...
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) provides $734,283 to Mayo Clinic to explore the relationships between circulating neuroactive steroid levels and alcohol use disorder (AUD), as well as AUD-related phenotypes. The project aims to measure the serum levels of allopregnanolone, its precursors, and isomers using gas chromatography coupled with mass spectrometry. This neuroactive...
- This Project Grant award, valued at $2,250,249.00 and funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports a research project conducted by the University of California, San Diego (UCSD) to investigate brain features associated with alcohol use disorder (AUD). The project aims to employ longitudinal multi-parametric magnetic resonance imaging (MRI) to assess baseline brain characteristics and changes following alcohol...
- This Project Grant award in the amount of $404,508.00 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The award aims to examine interleukin-1β (IL-1β) synaptic regulation and its role in cognitive impairment during early withdrawal and protracted abstinence from chronic alcohol exposure in male and female mice. The overarching goal is to determine the neuroimmune mechanisms by which chronic...
- This three-year, $855,106 project grant from the National Institute on Alcohol Abuse and Alcoholism will fund research at the Reed Institute examining the impact of gender identification and group dynamics on alcohol-related decision making among emerging adults ages 18 to 25. The grant aims to recruit 260 participants identifying as cisgender or gender diverse to participate in automated simulations and interviews exploring how social contexts like group size and gender composition influence...
This federal Project Grant award of $2,145,105 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) is funding research to investigate sex differences in the development of alcohol use disorder (AUD). The key objective is to examine how neuropeptidergic regulation of the bed nucleus of the stria terminalis (BNST) mediates the sex-dependent processing of alcohol's negative valence, which may contribute to the greater susceptibility of women to AUD. The funded research will utilize in vivo electrophysiology and optogenetic techniques to record BNST neural activity during a valence discrimination task, before and during acute alcohol withdrawal, to determine if females exhibit enhanced encoding of negative valence via the neurotensin receptor type 1 (NTSR1). This 4-year project aims to advance the understanding of the neurobiological mechanisms underlying the sex differences in the development of AUD, with the potential to inform the development of targeted interventions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.1m | 9/23/25 |