Project Grant R01AA031496
Award Date 9/5/25
Completion Date 8/31/29
Dollars Obligated $700K
Funding Federal Agency
Awarding Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New Mexico, USA
Similar Awards
- This federal Project Grant award of $119,253 from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) supports research to investigate the impact of third trimester alcohol exposure on memories encoded by sharp-wave ripples in the hippocampal-retrosplenial cortex circuit. The research will use a mouse model, in vivo electrophysiology, and optogenetics to examine how this alcohol exposure affects key features of sharp-wave ripples, such as amplitude...
- This federal Project Grant award, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports research to investigate the effects of chronic intermittent alcohol exposure on orbitofrontal cortex (OFC) astrocyte physiology, structure, and gene expression, and how these changes contribute to altered OFC neuron excitability and excessive drinking behaviors. The $459,707 award, with a period of performance from September 5,...
- This federal Project Grant award of $396,643 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) supports research to elucidate the mechanisms underlying stress-potentiated ethanol drinking. The project aims to investigate the role of the histone methyltransferase G9a and its effects on dynorphin-positive neurons in the nucleus accumbens to regulate this behavior. Key objectives include testing the hypothesis that G9a's effects on...
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) provides $248,959 to The Medical College of Wisconsin, Inc. to conduct research on the reciprocal relationship between alcohol use and brain function in adolescents and young adults. The 5-year project aims to assess how neurocognitive mechanisms of decision-making and risk-taking in adolescence contribute to alcohol use initiation, escalation, and maintenance,...
- This $1,039,420 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support research to study the neuronal ensembles and circuits involved in the facilitation and disinhibition of opioid and alcohol seeking behaviors. The 5-year project, which begins on June 1, 2025 and runs through February 28, 2030, will employ innovative techniques such as single-nucleus RNA sequencing, spatial sequencing, and in vivo...
- The Project Grant award of $657,156.00 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), supports research to examine the role of BK channels in alcohol-induced dysmyelination. The project aims to investigate the structural and functional correlates of myelin protein changes in a mouse model of alcohol use disorder, focusing on the effects of alcohol on oligodendrogenesis and pre-existing myelin. Key objectives include using...
- This federal Project Grant award, funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), will support research on the role of somatostatin in the central amygdala in relation to heavy alcohol drinking. The research team at Boston University Medical Campus will use an animal model of heavy alcohol drinking, combined with pharmacological, molecular, and electrophysiological approaches, to test the hypothesis that activation of...
- This Project Grant award, valued at $2,250,249.00 and funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), supports a research project conducted by the University of California, San Diego (UCSD) to investigate brain features associated with alcohol use disorder (AUD). The project aims to employ longitudinal multi-parametric magnetic resonance imaging (MRI) to assess baseline brain characteristics and changes following alcohol...
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) provides $3,168,729 to New York University to conduct a collaborative research project titled "A Translational Approach for Novel Precision Medicine Models." The project aims to identify novel molecular targets and mechanisms of treatment responses in alcohol use disorder (AUD) based on the role of mitochondrial metabolism and epigenetic...
- This federal Project Grant award of $539,237 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), supports research on a novel deep brain stimulation (DBS) approach that combines spike-timing dependent plasticity (STDP) to selectively modulate maladaptive neural plasticity associated with alcohol addiction and other neurological/psychiatric disorders. The project aims to apply precisely-timed STDP-DBS stimulation in two brain...