This $729,821 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program supports the development of artificial intelligence (AI) and machine learning (ML) methods for real-time monitoring and updating of clinical decision support (CDS) systems. The goal is to reduce health disparities that may arise from the use of CDS tools. The key products of this work include: Fair ML models trained on retrospective...
This Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) federal grant program provides $249,000.00 in funding from August 1, 2025 to July 31, 2028 to Vanderbilt University Medical Center (VUMC). The grant supports the development and implementation of advanced statistical machine learning methods to shorten the diagnostic and therapeutic "odysseys" faced by patients with rare diseases. Key...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Medical Library Assistance (CFDA 93.879) federal grant program, will fund the development and validation of a clinically reliable and transparent large language model (LLM)-based question-answering (QA) system and a clinical chatbot for decision support in emergency department (ED) settings. The total funding amount is $176,068.00, with an award date of September 1, 2024, and an expected...
This $375,964 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program aims to address the issues of factual inaccuracy and unfaithful reasoning in large language models (LLMs) applied to biomedical and healthcare domains. The key objectives are to: (1) establish a self-augmentation framework to enable LLMs to automatically select and use relevant biomedical digital resources; (2) develop an LLM curator...
This federal Project Grant award, funded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program, aims to develop and validate a novel informatics framework to extract computable population, intervention, comparison, and outcome (PICO) elements and summarize them from publications of interventional and observational studies. The total funding amount is $391,388.00, with an award date of September 18, 2024 and an ultimate...
This federal Project Grant award for $1,312,212 from the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program will support research to develop an advanced DNA language model. The primary goal is to use natural language processing techniques to better understand the role and functionality of DNA sequences, especially non-coding regions, which could lead to advancements in areas like genetic testing and personalized medicine. The...
This $997,678 Project Grant, awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Medical Library Assistance (CFDA 93.879) program, will fund the development of automated methods to standardize and enhance the metadata contained within major biomedical databases, such as the Sequence Read Archive (SRA) and Gene Expression Omnibus (GEO). The grant, awarded to the University of Wisconsin System, will leverage advanced machine learning, natural language processing,...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $306,872 Project Grant (CFDA 93.113 - Environmental Health) to Pico Portal, Inc. to develop and evaluate advanced AI-driven tools to automate, increase efficiency, and reduce the costs of conducting risk-of-bias (ROB) assessments in environmental health systematic reviews. Specifically, the project aims to utilize large language models to accurately identify and extract critical text passages related to per- and...
The National Institute of General Medical Sciences (NIGMS) awarded a $780,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Colorado-Denver. The 5-year grant, effective September 10, 2024, supports the Cole Lab's research to develop novel methods and expand resources that improve the derivation and utilization of environmental phenotypes for human disease research. Key focus areas include: 1) optimizing phenotype pre-processing using...
This federal Project Grant award of $500,000.00 was made on September 30, 2024 by the Agency for Healthcare Research and Quality (AHRQ) under the Research on Healthcare Costs, Quality and Outcomes (CFDA 93.226) program. The grant was awarded to Brigham & Women's Hospital Inc., a subsidiary of the larger Partners Healthcare System Incorporated, to conduct research on the relationships between diagnosis quality, clinician time and stress. The key objectives of the 4-year project are to: 1)...