This Project Grant award, funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program, aims to investigate the neural mechanisms driving adaptive stress coping behaviors and subsequent alcohol use. The $498,121.57 award, effective August 15, 2024 through July 31, 2027, will utilize an animal model to explore how dysfunction in the corticolimbic circuitry, specifically the prelimbic cortex and basolateral...
This $194,400 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, will support research on the effects of adolescent alcohol use on the oral microbiome and brain. The awardee, the Medical University of South Carolina, will recruit 126 adolescents (ages 14-18) with varying levels of alcohol use to collect salivary samples to assess the oral microbiome, with a focus on the Lactobacillus...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) program, provides $499,442 in funding to The Regents of the University of California, San Francisco (UCSF) from August 20, 2024 through July 31, 2027. The award supports research to investigate the role of brain-derived neurotrophic factor (BDNF) signaling in the ventral hippocampus and its contribution to the acute anxiolytic and social...
This federal Project Grant award of $1,135,243 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) will support research to investigate changes in neural mechanisms associated with cognitive reappraisal and alcohol cue reactivity during early abstinence from alcohol use disorder (AUD) treatment. The research, conducted by the University of Colorado-Denver and involving sub-awards to Emory University and the University of Denver,...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, will support the development of novel 3D human brain circuits to investigate the role of microglia in alcohol use disorder (AUD) and Alzheimer's disease (AD) pathology. The $223,531 award to the University of North Carolina at Chapel Hill will fund research to elucidate how alcohol-induced changes in microglial metabolism...
This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), provides $249,000.00 to the University of North Carolina at Wilmington to investigate how adolescent binge drinking impacts the integration of newborn neurons into mature hippocampal circuitry. The research aims to elucidate the cellular and physiological mechanisms by which adolescent alcohol exposure disrupts the maturation and circuit integration...
This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, will support the development and testing of a novel in vivo model called CHIMERA-BONCAT. This model will enable comprehensive, unbiased, and cell-type-specific characterization of the human microglial response to alcohol exposure. The $214,385 award, with a period of performance from August 2024 to July 2026, will fund research...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA, CFDA 93.273 Alcohol Research Programs) provides $156,204.00 to the University of Massachusetts Medical School to investigate the role of BNST PKCdelta neurons in compulsive ethanol intake. The key focus is to evaluate adaptations in BNST PKCdelta neuron activity across abstinence periods and in response to ethanol exposure, as well as explore how dysregulation in BNST PKCdelta neuron afferents...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $597,000 Project Grant under the Alcohol Research Programs (CFDA 93.273) to The Pennsylvania State University (Penn State) to conduct research on the effects of adolescent binge drinking on behavioral profiles, somatostatin neuron function, and functional connectivity in the prefrontal cortex. The research aims to characterize sex-specific, long-term impacts of adolescent alcohol exposure on cortical signaling and brain...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $736,668 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Southern California to conduct a multi-method investigation of social facilitation of alcohol effects and alcohol misuse in young adults. The project aims to extend prior research on the phenomenon of social facilitation of alcohol effects, exploring predisposing factors and mechanisms. This will involve laboratory-based studies...