Project Grant R00AA030089
- This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA, CFDA 93.273 Alcohol Research Programs) provides $647,330 to Wake Forest University Health Sciences to conduct research on the role of epigenetics in predisposing the brain to risky alcohol use. The researchers will perform a longitudinal genome-wide DNA methylation analysis of the rhesus macaque dorsolateral prefrontal cortex to identify biomarkers associated with future alcohol drinking levels. The goal...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the U.S. Department of Health and Human Services, awarded a $150,526 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Board of Regents of the Nevada System of Higher Education, doing business as the University of Nevada, Las Vegas (UNLV). The project aims to assess the prevalence and theoretical drivers of novel high-intensity drinking behaviors, such as "BORG" (blackout rage gallon) drinking,...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $733,704 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Lovelace Biomedical Research Institute in Albuquerque, New Mexico. The grant, titled "Multimodal Imaging of Prenatal Alcohol Exposure: Mechanisms Underlying Spatial Navigation Memory Deficits in Children and Adolescents," will fund a study to advance understanding of the neurophysiological mechanisms underlying spatial memory...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $550,417 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Texas at Austin. The grant, effective September 1, 2025 through May 31, 2030, supports research to investigate how heavy alcohol exposure in aging individuals leads to impaired microglia function, neurodegeneration, and cognitive deficits. The study aims to determine whether dysregulated neuroimmune and microglia responses are...
- This federal Project Grant award for $700,000.00, issued by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program, supports research to investigate the neurophysiological and genetic factors contributing to binge drinking and alcohol use disorder. The primary awardee, the University of New Mexico (UNM) Health Sciences Center, will leverage techniques such as monosynaptic circuit labeling, optogenetics, electrophysiology,...
- This federal Project Grant award of $119,253 from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) supports research to investigate the impact of third trimester alcohol exposure on memories encoded by sharp-wave ripples in the hippocampal-retrosplenial cortex circuit. The research will use a mouse model, in vivo electrophysiology, and optogenetics to examine how this alcohol exposure affects key features of sharp-wave ripples, such as amplitude...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), awarded a $121,887 project grant to the University of North Carolina at Chapel Hill to identify the neurophysiological phenotypes that contribute to alcohol-related blackout susceptibility. The project, running from January 31, 2025 to August 31, 2027, aims to investigate the role of GABAergic inhibition and functional connectivity patterns in predisposing individuals to...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $136,236 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Washington on January 25, 2025. The grant project aims to investigate the synergistic effects of chronic alcohol use and pathological tau expression in a preclinical model, in order to better understand the neurodegeneration processes underlying Alzheimer's disease and related dementias (ADRD). Specifically, the research will...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a 5-year, $597,000 Project Grant titled "Sex-Dependent Shifts in Behavioral Profiles and Cortical Signaling Following Adolescent Binge Drinking" to The Pennsylvania State University. The grant, funded under CFDA 93.273 Alcohol Research Programs, aims to characterize changes in behavior, cortical adaptations in somatostatin neuron function and peptide signaling, and functional connectivity following adolescent...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $105,132 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Kentucky Research Foundation. The grant, titled "Uncovering the Functional and Mechanistic Dysregulation of Monocytes After Abstinence and Post-Abstinence Drinking," will leverage a rhesus macaque model to investigate the persistent functional, transcriptional, and epigenetic changes in peripheral monocytes induced by...
The University of North Carolina at Wilmington (UNCW) received a $249,000 Project Grant award on Mar 10, 2025 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The grant supports a research project titled "Adolescent Intermittent Ethanol Induction of Neuroimmune Signaling Disrupts the Mature Phenotype of Surviving Hippocampal Neuroprogenitors" that aims to investigate how adolescent binge drinking affects the integration of newborn neurons into the adult hippocampal circuitry. The project will use a transgenic mouse model to track the long-term impacts of adolescent alcohol exposure on neuroprogenitor cells and neuroinflammatory signaling, with the goal of better understanding the mechanisms underlying the persistent cognitive deficits associated with adolescent binge drinking.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 7/21/25 | ||
| Not listed | $249.0k | 7/8/25 |