Project Grant P50MH143668
- The National Institute of Mental Health awarded Butler Hospital $781,566 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop RESTEPS, a suicide prevention intervention for youth with first-episode psychosis transitioning from acute care to outpatient treatment. The study addresses a critical gap: youth with first-episode psychosis face elevated suicide risk during care transitions, yet clinical trials of suicide-focused interventions routinely exclude...
- The National Institute of Mental Health awarded the University of California, San Diego $793,814 on June 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop and evaluate Recovery Integrated Safety and Engagement (RISE), a peer-supported suicide prevention intervention for individuals at clinical high risk for psychosis. The award funds a three-year hybrid Type 1 pilot study at two sites following the Exploration, Preparation, Implementation, Sustainment framework....
- The National Institute of Mental Health awarded the University of Pittsburgh $458,433 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop, refine, and validate a developmentally-tailored and ecologically-valid adolescent emotional faces stimulus set and examine the extent to which adolescents' socioaffective processing of these stimuli predicts unique variance in symptoms of anxiety, depression, suicidal ideation, and lifetime history of suicidal...
- The National Institute of Mental Health awarded the University of Illinois $100,228 on September 30, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct qualitative research on implementation of suicide prevention evidence-based practices in outpatient pediatric behavioral health settings. The recipient will recruit pediatric mental health clinicians, youth patients ages 12–18, and patient caregivers from public outpatient child psychiatry clinics to participate in...
- The National Institute of Mental Health awarded the University of Alabama at Birmingham $726,339 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct a hybrid randomized effectiveness-implementation trial of THRIVE, a recovery-focused suicide prevention intervention for crisis stabilization centers. THRIVE is a suicide recovery and care transitions program combining a belonging, giving, and recovery psychotherapy group during crisis stabilization...
- The National Institute of Mental Health awarded the University of Connecticut $377,144 on August 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop and test CHISSA, a smartphone app-based just-in-time adaptive intervention (JITAI) designed to identify suicide risk and deliver tailored interventions for homosexual cisgender men in Nepal. The award supports research applying the discover-design-build-and-test (DDBT) model to adapt and refine features of existing...
- The National Institute of Mental Health awarded the University of California, San Diego $199,271 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop a measurement-informed machine learning model for generalizable suicide risk prediction in youth. The project will create a transparent, interpretable, and developmentally sensitive machine learning model incorporating neurobiological, psychological, electronic health record-derived, and social indicators to...
- The National Institute of Mental Health awarded the University of Wisconsin - Madison $747,342 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct an examination of social connection in suicide risk during the college transition. The project leverages multimodal, high-resolution assessments to elucidate how social connection across digital and physical contexts contributes to suicide risk during the transition to college. The research will collect...
- The National Institute of Mental Health awarded The General Hospital Corporation (Massachusetts General Hospital) $824,404 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop machine learning models that integrate clinician-conducted suicide risk assessments with electronic health record data to improve prediction of suicidal behavior and guide precision interventions in outpatient behavioral health settings. The research leverages routine clinical...
- The National Institute of Mental Health awarded the University of Pittsburgh $437,250 on June 5, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct a longitudinal feasibility study examining the association between childhood gender nonconformity and early indicators of risk for suicidal behavior among children ages 7–10. The study collects data on psychosocial stressors, biological dysregulation in the hypothalamic-pituitary-adrenal axis and inflammatory pathways,...
The National Institute of Mental Health awarded the University of Pennsylvania $2.483 million on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to establish the Innovation in Suicide Prevention Research Center (INSPIRE), a research center focused on developing and scaling evidence-based suicide prevention interventions for youth and young adults. INSPIRE will develop and adapt practical suicide prevention interventions for youth and young adults and employ advanced technologies and implementation strategies to optimize delivery at scale with high fidelity in acute care and community practice settings. The center will deploy generative artificial intelligence, electronic health record research, applied informatics, fusion trials, emulated trial design, biostatistics, qualitative and mixed-methods research, cost evaluation, effectiveness-implementation trials, and human-centered design. The signature project will compare the effectiveness of three interventions: the Supporting Transitions to Adulthood to Reduce Suicide (STARS) program, which includes the Safety Planning Intervention and peer mentoring supported by a digital app; STARS+, which adds near real-time feedback; and Safety Planning Intervention alone, measuring effects on suicidal ideation, attempts, and preliminary implementation outcomes. Three exploratory projects will examine implementation of other evidence-based interventions in pediatric emergency departments and community settings. The award runs from September 1, 2026, through July 31, 2031, with place of performance in Philadelphia, Pennsylvania.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.5m | 8/21/26 |