This $2,372,456 Project Grant award from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393) supports research to leverage observational (real-world) data to advance precision oncology. The principal investigator is Charles Sawyers of Memorial Sloan Kettering Cancer Center. The project has four integrated components: 1) overcoming methodologic barriers in analyzing observational clinico-genomic data, 2) addressing the role of genetic ancestry in precision oncology outcomes, 3) using real-world evidence to inform clinical treatment decisions, and 4) optimizing the reporting of findings using the OncoKB knowledge base. Key sub-awards support this work at Dana-Farber Cancer Institute, University of California San Francisco, and Morehouse School of Medicine. The award period is from Sep 3, 2024 to Aug 31, 2029.
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