Federal Grant Award Summary

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $2.72 million Project Grant on June 12, 2026, to the University of Washington for a five-year research initiative titled "A Multi-Tissue Temporal Framework for TH2 Responses" (completion date: May 31, 2031). This award falls under the Allergy and Infectious Diseases Research program (CFDA 93.855) and supports investigator-initiated biomedical research on Type 2 immune responses across multiple tissue environments.

The research program delivers scientific knowledge and mechanistic insights into how Type 2 immunity is initiated, maintained, and recalled across barrier tissues—specifically the small intestine, skin, large intestine, and lungs. The project comprises four interdependent sub-projects that collectively address neuro-immune circuit regulation, allergic sensitization pathways, inflammatory niche formation, and tissue-resident memory populations. Through harmonized methods and shared resources, the research generates discoveries applicable to understanding both helminth defense mechanisms and chronic allergic disease pathology (including asthma, eczema, and food allergy), while advancing fundamental immunological understanding through cross-tissue comparative analysis and identifying conserved versus tissue-specific principles governing Type 2 inflammatory responses.