Project Grant K99NS138587
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025 for $1,180,687. The purpose of this 8-year project is to investigate how neural stem cell niches transition from embryonic to postnatal stages in the human forebrain, with a focus on characterizing the different neural...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $1,008,977.00 to the Regents of the University of California, San Francisco to conduct research on the developmental topology of the human cerebral cortex. The key objectives are to understand human brain development and the origins of neurodevelopmental diseases by studying...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $125,724 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on January 23, 2025. The project, titled "Hypoxia-Induced Misdirection: Understanding Postnatal Inhibitory Interneuron Migration in Neonatal Hypoxic Injury", aims to use computational approaches to identify altered...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), provides $381,375.00 to New York University to develop genetic strategies to study a novel disinhibitory system in the cortex. Specifically, the project aims to gain a detailed understanding of how top-down and bottom-up signals are integrated in the superficial...
- This federal Project Grant award of $457,714 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at the University of California, Davis (UC Davis) to uncover the dynamics of microRNA (miRNA) expression and the mRNAs targeted by miRNA pairs in neural progenitors over time. The goal is to define the miRNAs and their target mRNAs involved in cortical cell...
- This federal Project Grant award of $629,796 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award aims to track, quantify, and localize key metabolic pathways that regulate brain growth during development. Specifically, the project will investigate two critical metabolic switches in the developing mouse brain: (1) a shift from glycolytic to...
- This federal Project Grant award, ID R35NS137247, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award totaling $1,174,913.00 supports research to understand the fundamental mechanisms of homeostatic plasticity, a compensatory process that stabilizes neural function, and its potential links to neurodevelopmental disorders such as autism and...
- This federal Project Grant award of $606,548.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a new recording modality called "mesoscopic electrophysiology" for non-human primates. The goal is to create a system that combines the large field of view and spatial resolution of fMRI with the temporal resolution of...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research to investigate the role of inhibitory synaptic nanostructure in inhibitory synaptic plasticity. The total award amount is $110,574.00 and the period of performance is from July 14, 2025 to November 30, 2027. The research will be conducted by the University of Colorado-Denver,...
- This $691,935 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders supports research to develop quantitative diffusion MRI methods for predicting neurodevelopmental outcomes in infants with hypoxic ischemic brain injury. The project aims to analyze diffusion MRI data from two large datasets - the High-Dose Erythropoietin for Asphyxia and Encephalopathy (HEAL)...
This federal Project Grant award of $115,327.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research to investigate the protracted maturation of cortical inhibitory neurons (CINs) in the human brain and their contribution to regional cortical specification and vulnerability during the perinatal period. The research aims to elucidate how the migration of immature CINs into the cingulate and temporal cortices impacts the development of higher cognitive functions and the risks for disorders like autism spectrum disorder. This work utilizes comparative analyses of human, chimpanzee, and piglet brains to study the distinctive CIN migration patterns in the gyrencephalic human brain. The award period runs from Aug 11, 2025 to Jul 31, 2027 and is being carried out by the Regents of the University of California, San Francisco, a prominent academic medical center and research institution.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $115.3k | 8/11/25 |