Project Grant K99MH139728
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a Project Grant in the amount of $608,086 under the Mental Health Research Grants program (CFDA 93.242) effective March 24, 2026 through December 31, 2029. The research project, titled "The Functions of the Claustrum in Flexible Decision Making," investigates the neurobiological mechanisms underlying cognitive flexibility and decision-making processes in the brain. The funded...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Trustees of Columbia University in the City of New York a Project Grant of $126,900 under the Mental Health Research Grants program (CFDA 93.242) for research extending from April 2, 2026, through March 31, 2028. This award funds basic neuroscience research investigating the cellular and circuit mechanisms underlying value representation in the mouse medial prefrontal cortex (mPFC), a brain region essential...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a Project Grant totaling $149,190 under the Mental Health Research Grants program (CFDA 93.242) on August 2, 2026, with completion targeted for February 1, 2027. This research initiative, titled "Identifying Intervention Opportunities in the Continuum of Cognitive Impairment Among Persons Aging with HIV," produces epidemiological research and evidence synthesis designed to...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a Project Grant of $443,931 under the Mental Health Research Grants program (CFDA 93.242) for the period July 1, 2025 through June 30, 2027. This research project aims to develop and validate novel methodologies for accurately tracking structural brain changes using low-field (0.05T) magnetic resonance imaging (MRI) technology coupled with autonomous control systems and...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a $804,690 Project Grant under the Mental Health Research Grants program (CFDA 93.242), effective June 12, 2025 through April 30, 2030. This research project investigates the relationship between N-acetyl-aspartyl-glutamate (NAAG), a peptide neurotransmitter, and memory deficits in schizophrenia patients in mid- to late-life. The primary deliverable involves measuring NAAG levels using...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Pittsburgh a Project Grant of $1,004,971 under the Mental Health Research Grants program (CFDA 93.242) on April 8, 2026, with a completion date of February 28, 2029. The award supports the development of an integrated research platform designed to measure and analyze brain activity, cognitive states, behavior, and physiology in real-world settings. The project leverages a unique clinical...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a $197,640 Project Grant effective September 1, 2025 through August 31, 2030 under the Mental Health Research Grants program (CFDA 93.242). This five-year award supports an early-career investigator's research into schizophrenia-associated genetic variants in the GRIA3 gene, which encodes GluA3, a critical subunit of the AMPA receptor (Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Johns Hopkins University a $183,056 project grant effective June 15, 2025, through May 31, 2029, under the Mental Health Research Grants program (CFDA 93.242). Principal investigator Dr. Catherine Ettman will conduct a comprehensive research investigation examining the relationship between economic precarity, clinical operations features, and psychiatric appointment continuity in patients with depression....
- Federal Grant Award Summary The University of California, San Diego received a $415,664 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on March 15, 2026, with a completion date of December 31, 2030. This award funds basic neuroscience research investigating the neurophysiological mechanisms underlying value-based decision-making through the study of distinct orbitostriatal circuits. The research utilizes...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Pennsylvania a $221,302 Project Grant on March 1, 2026, under the Mental Health Research Grants program (CFDA 93.242). This two-year exploratory research project (R21 grant mechanism) aims to systematically assess the impact of mandatory National Institutes of Health (NIH) neuroethics requirements on the ethical design and conduct of brain-related human subjects research. The primary deliverables...
The National Institute of Mental Health (NIMH) awarded a Project Grant totaling $104,349.00 to The Johns Hopkins University (Award Date: April 1, 2026; Completion Date: March 31, 2028) under the Mental Health Research Grants program (CFDA 93.242). This research project, titled "Attentional Modulation of Neural Activity in Multi-Attribute Decision Making," investigates the neural mechanisms underlying complex, real-world decision-making processes. The primary deliverables include development of a computational model for attention-modulated multi-attribute decisions (AM-MAD) and empirical findings from neuronal activity recordings conducted in both non-human primate subjects (macaques) and human patients undergoing intracranial epilepsy treatment. The research employs a novel experimental task design that isolates individual attributes of decision options presented sequentially, enabling researchers to monitor attentional focus and neural responses throughout the decision-making process. Key products include peer-reviewed publications documenting findings from pre-supplementary motor area (pre-SMA) neurons that encode action value signals and demonstrate how attentional focus modulates value representation. The work leverages comparative neuroscience data across species and clinical populations to advance mechanistic understanding of decision-making processes, with potential applications for treating cognitive and behavioral disorders associated with decision-making deficits.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $104.3k | 3/27/26 |