This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $787,584 to the University of North Carolina at Chapel Hill (UNC-CH) for a 5-year research project beginning December 1, 2024. The project aims to characterize the neural and behavioral trajectories of executive function (EF) from infancy to early adulthood, and to examine how these trajectories relate to the development of psychopathology....
This federal Project Grant award of $794,931 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will fund a longitudinal study on the relationship between early parent-infant synchrony and later childhood outcomes among infants at genetic risk for ADHD or autism spectrum disorder (ASD). The study will leverage 3 existing cohorts of 326 infants previously enrolled in the PI's prior NIMH-funded studies, who will be followed from 6...
The National Institute of Mental Health (NIMH) awarded a 5-year, $857,216 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Children's Hospital Corporation (doing business as Boston Children's Hospital) to study the neurodevelopmental trajectories leading to early symptoms of Attention Deficit Hyperactivity Disorder (ADHD) and disruptive behaviors in socioeconomically disadvantaged, racially and ethnically diverse children. The key objectives of this project are to: 1)...
The National Institute of Mental Health (NIMH) awarded a $392,500 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to the Research Institute at Nationwide Children's Hospital. The 2-year award, beginning May 1, 2025, will fund research to characterize the role of sleep brain dynamics in the emergence of depression in adolescents. The study aims to: 1) identify the space-time profiles of slow oscillations and sleep spindles and compare them across youth at high and...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $2,504,682 to Yale University to conduct research examining the links between the neonatal connectome and dimensions of social development. The study aims to prospectively investigate associations between the infant functional brain network characteristics and later social attention and engagement outcomes in a sample of infants with and without...
The National Institute of Mental Health (NIMH) awarded a $1,453,943 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of California, Los Angeles (UCLA) for the period of June 1, 2025 to May 31, 2028. The grant will fund the development of an integrated, portable sensor suite to concurrently record neural activity, physiological arousal, motor signals, and physical interactions in social environments. The project aims to track neuro-behavioral attention...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, provides $746,183 to the University of South Carolina to conduct a prospective, longitudinal study on neonatal autonomic nervous system (ANS) dysfunction as a predictor of autism spectrum disorder (ASD) in preterm infants. The study aims to: 1) evaluate preterm ANS dysfunction as an ASD-specific etiological mechanism, 2) examine how neonatal morbidities...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will fund a 5-year study to examine the relationship between parent-child neurobehavioral synchrony and early trajectories of Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms in preschool-aged children. The $673,803 award, starting on December 1, 2024, will support the University of Pittsburgh in using functional near-infrared spectroscopy (fNIRS)...
The National Institute of Mental Health (NIMH) awarded a $1,380,070 Project Grant (CFDA 93.242 - Mental Health Research Grants) to Duke University to explore the cellular properties and circuit functional roles of human cortical interneurons. This research aims to generate a multimodal phenotypic catalog of human interneurons and characterize their functional organization in neural circuits. The project will utilize live brain specimens collected from neurosurgical procedures and a novel genetic...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $375,927 to the Rector & Visitors of the University of Virginia (UVA) to conduct research on the impact of premature birth and serotonin signaling on the development of the prefrontal cortex. The research aims to mechanistically determine how the timing of birth and serotonin levels affect intrinsic neural activity and the establishment of...
The National Institute of Mental Health (NIMH) awarded a Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Duke University in the amount of $197,660 with a project period from Sep 4, 2024 to Aug 31, 2026. The project aims to characterize early signs of neurobehavioral dysregulation in infants at increased risk for behavioral disorders, such as children with prenatal nicotine exposure. The research will leverage integrative data analysis techniques to identify modifiable mechanisms that increase risk for behavior dysregulation in toddlers, and track trajectories of attention, motor, and sleep behavior in the first postnatal year to pinpoint risk for later behavior dysregulation. The findings are expected to aid in prevention and intervention efforts by isolating early mechanisms of risk and identifying malleable behavioral targets, aligning with NIMH's strategic priorities.