Project Grant K99HD120649
- This $429,000 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) supports research to investigate the gene and environmental influences on placental angiogenesis and severe fetal growth restriction. The 2-year project, awarded to the University of Colorado-Denver, leverages induced pluripotent stem cell technology to study the development of placental vasculature and...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $133,401 Project Grant under CFDA 93.865 - Child Health and Human Development Extramural Research program to the Fred Hutchinson Cancer Center in Seattle, WA. The grant, awarded on September 1, 2025, supports the development of computational models to analyze the coordination between changes in gene expression and chromatin accessibility during cellular differentiation and maturation. The...
- This $163,145 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the role of microRNAs in placental development and fetal growth restriction (FGR). The principal investigator will model metabolic stress associated with FGR by culturing extravillous trophoblasts in nutrient-restricted media, and analyze the...
- This Project Grant award was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865). The $429,000 award to Oregon Health & Science University will support research to analyze placental cell-specific extracellular vesicle (EV) RNA cargo throughout human gestation. The goal is to better understand the contributions of the placenta to normal...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $293,550 Project Grant to Seattle Children's Hospital, doing business as Seattle Children's Research Institute, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant, awarded on September 5, 2025, will fund research to investigate the effect of inherited maternal cells on BCG-specific T cell responses in HIV-exposed and unexposed infants. The...
- This federal Project Grant award of $760,617 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to understand the mechanisms underlying the transition of epiblast cells through different pluripotent states during peri-implantation development. The project aims to elucidate the molecular, cellular, and epigenetic events that occur during this...
- This Project Grant award of $249,000.00 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to understand the impact of fetal growth restriction (FGR) on the development of non-communicable diseases like cardiovascular disease, hypertension, obesity, and diabetes. The award, with a performance period from July 1, 2025 to June 30, 2028, will...
- The National Institute of Child Health and Human Development (NICHD), through the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded a $661,258 Project Grant to the University of Washington to support a multi-faceted initiative aimed at improving the clinical evaluation and data collection for stillbirth, advancing tools to evaluate maternal-fetal interface immune biology and detect placenta dysfunction, and developing novel models to predict an individual's...
- This $178,000 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to develop an early life phenotyping framework for very preterm infants. The research aims to create 'perinatal phenotypes' by integrating variables such as reason for preterm birth, intrapartum care, and neonatal presentation, and then determine how these phenotypes contribute to...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), is providing $226,608 to the University of Colorado-Denver to assess the mechanism by which fetal glucagon inhibits placental nutrient transfer. The objective is to identify the link between fetal glucagon and placental nutrient delivery as an adaptive mechanism to match...
This $259,076 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to understand the role of prenatal nutrition in placental gene regulation and spontaneous preterm birth. The principal investigator at Seattle Children's Hospital, doing business as Seattle Children's Research Institute, will build a genome-scale nutrient regulatory network of the human placenta and leverage it to identify nutrient mixtures associated with spontaneous preterm birth. The research aims to address knowledge gaps on how nutrient-gene interactions influence placental biology and pregnancy outcomes. This 2-year project, with a start date of September 24, 2025, will involve collaboration with a multidisciplinary mentorship team to execute the research plan.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $259.1k | 9/23/25 |