The National Eye Institute (NEI) awarded a $132,597 Project Grant under the Vision Research federal grant program (CFDA 93.867) to The Schepens Eye Research Institute, Inc., a non-profit organization affiliated with Harvard Medical School and Massachusetts Eye and Ear. The grant supports research to investigate the role of neural activity in regulating the integration of transplanted retinal ganglion cells (RGCs) within the host retina, with the goal of improving functional connectivity and outcomes for RGC replacement therapies targeting glaucoma. The project aims to characterize retinal remodeling following RGC inactivation and determine if inhibiting host neural activity can enhance structural and functional integration of donor RGCs. The award spans the period from February 1, 2025 to January 31, 2026. The institute has substantial experience conducting vision research through prior federal grants and sub-awards totaling over $35 million.
Generated 3/4/25, 4:14 AM