Project Grant K99CA312830
Award Date 6/1/26
Completion Date 5/31/28
Dollars Obligated $161K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Boston, MA 02114, USA
Similar Awards
- Federal Grant Award Summary The National Cancer Institute awarded a $176,040 Project Grant to Massachusetts General Hospital under the Cancer Research Manpower program (CFDA 93.398) effective July 1, 2025 through June 30, 2027. The award funds research to develop engineered CAR-T (Chimeric Antigen Receptor T) cell therapies capable of overcoming the cancer cell glycocalyx barrier, a protective layer that impedes immune cell recognition and destruction of solid tumors. The research addresses a...
- Federal Project Grant Award Summary Massachusetts General Hospital (MGH), through its Research Management Division, received a $707,798 project grant from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396), effective April 1, 2026 through March 31, 2031. The award funds research to determine mechanisms of heterogeneous treatment response in glioblastoma (GBM), an aggressive brain tumor that typically recurs in treatment-refractory form shortly after...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded Massachusetts General Hospital a $659,201 Project Grant effective June 1, 2026 through May 30, 2031 under the Cancer Treatment Research program (CFDA 93.395). This award supports research investigating the integrated stress response (ISR) in glioblastoma (GBM) pathogenesis and therapeutic response. The project focuses on understanding how the interplay between phosphorylated eukaryotic translation initiation factor 2A...
- Federal Grant Award Summary Massachusetts General Hospital received a $684,107 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) awarded on August 18, 2025, with a completion date of July 31, 2030. The grant supports research into the integration of circulating tumor cell (CTC) and nuclear imaging biomarkers to assess response and resistance to prostate-specific membrane antigen (PSMA) radiopharmaceutical therapy (RPT) in...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded Massachusetts General Hospital a $195,240 Project Grant under the Cancer Research Manpower program (CFDA 93.398) effective September 17, 2025, through August 31, 2030. This K25 career development award supports the development of an innovative single-cell assay platform that correlates genome, transcriptome, and dynamic behaviors of metastatic cancer cells using laser particles (LPs)—biocompatible optical barcoding...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded $188,080 to Massachusetts General Hospital under the Cancer Research Manpower program (CFDA 93.398) on August 22, 2025, for a mixed-methods research study examining barriers and facilitators to tertiary referral for complex pancreatic cancer surgical care. The project, which will conclude August 21, 2027, addresses the critical gap between surgical eligibility and utilization in early-stage pancreatic cancer...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a Project Grant totaling $901,205 to Boston Children's Hospital under the Cancer Treatment Research program (CFDA 93.395) effective July 3, 2025, with a completion date of June 30, 2032. This research initiative focuses on identifying genome-wide changes in gene expression during early tumorigenesis and metastatic progression to improve immunotherapy efficacy. The project leverages genetically engineered mouse models...
- Federal Grant Award Summary The National Cancer Institute awarded a $700,838 Project Grant to The Regents of the University of California, San Francisco under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) for a five-year period beginning April 1, 2026. This award supports research to develop and optimize a Magnetic Resonance (MR) multi-tasking abdominal integrated imaging system (MT-AI2) capable of providing clinically accessible voxel-level liver functional assessment for...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a $409,141 Project Grant to the University of California, Davis under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) for the period June 1, 2026 through May 31, 2028. The project, titled "Perfusion CT for Liver Radioembolization," aims to develop and validate contrast-enhanced perfusion computed tomography (CT) imaging as an alternative diagnostic approach for treatment planning in selective...
- Federal Grant Award Summary The National Cancer Institute awarded a $736,168 Project Grant to Sloan-Kettering Institute for Cancer Research (award date: August 1, 2025; completion date: July 31, 2030) under the Cancer Treatment Research program (CFDA 93.395) to develop novel antibody-drug conjugates (ADCs) and antibody-oligonucleotide conjugates (AOCs) designed to enhance radiotherapy efficacy through antigen-specific radiosensitization. The research focuses on delivering potent DNA damage...