The National Cancer Institute (NCI) awarded a $173,997 Project Grant under the Cancer Research Manpower (CFDA 93.398) federal grant program to Duke University. The funding will support a pilot randomized controlled trial to assess the feasibility, acceptability, and outcome patterns of the NITE2DAY+ intervention, which aims to improve insomnia, fatigue, distress, and pain symptoms in hematologic cancer patients during and after inpatient treatment. The NITE2DAY+ intervention incorporates...
This Project Grant award from the National Institute on Drug Abuse (NIDA), funded under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to investigate how cognitive-behavioral therapy for insomnia (CBT-I) can improve emotion regulation, self-control, and smoking cessation outcomes among adults who smoke. The $936,880 award, granted to Yale University, will fund a randomized controlled trial to examine the neural mechanisms underlying the effects of CBT-I on attentional bias,...
The National Cancer Institute (NCI) awarded a $968,999 Project Grant under the Cancer Cause and Prevention Research (CFDA 93.393) program to the University of North Carolina at Chapel Hill (UNC-CH) to optimize imaging-based surveillance strategies for lung cancer survivors. The 5-year project aims to develop and validate risk prediction models that incorporate novel imaging biomarkers from routine CT scans to personalize post-treatment surveillance and detect recurrent or new lung cancer at...
This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $402,401.00 to the University of Missouri System to pilot test a Metacognitive Strategy Training (MCST) intervention aimed at addressing cancer-related cognitive impairment in breast cancer survivors. The study will assess the feasibility and impact of MCST on cognitive performance, frontoparietal neural activation, and functional connectivity in a sample of 50 participants. Key...
This federal Project Grant award from the National Institute of Nursing Research (CFDA 93.361 Nursing Research) provides $827,766 to the University of Miami to conduct a study on a dyadic sleep intervention for patients with GI cancer and their caregivers. The "My Sleep Our Sleep" (MSOS) intervention aims to improve sleep quality for both the patient and their caregiver who share the same bed. The study will test the preliminary efficacy of the MSOS intervention against a brief...
The National Cancer Institute (NCI) has awarded a $621,732 project grant under the Cancer Cause and Prevention Research (CFDA 93.393) program to The Medical University of South Carolina (MUSC). The grant will fund a 5-year hybrid effectiveness-implementation trial to evaluate a proactive identification and digital mental health intervention approach to address unmet psychosocial needs of individuals living with likely incurable cancer. The key products and services to be delivered through this...
This federal Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), provides $737,480.00 to The Regents of the University of California, San Francisco (UCSF) to conduct feasibility and acceptability testing of an integrated cognitive behavioral therapy for insomnia (CBT-I) and passive body heating (PBH) intervention. The overarching goal is to develop and...
This Project Grant award from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395) supports the adaptation and preliminary evaluation of the ENERGIZE-MBC cognitive behavioral therapy (CBTF) intervention for managing fatigue among women with metastatic breast cancer treated with CDK4/6 inhibitors. The $638,326 award to the H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc. will fund a clinical trial planning project to: 1) adapt the CBTF...
This federal Project Grant award from the National Cancer Institute's Cancer Research Manpower (CFDA 93.398) program provides $293,053 to The General Hospital Corporation (Massachusetts General Hospital) to refine and pilot test a psychosocial intervention incorporating Acceptance and Commitment Therapy to address the unmet supportive care needs of patients with primary malignant central nervous system tumors. The 5-year project aims to 1) refine the population-specific intervention,...
The National Cancer Institute (NCI) awarded a $256,487 Project Grant under the Cancer Research Manpower (CFDA 93.398) program to the Sloan-Kettering Institute for Cancer Research in New York, NY. The grant supports a 5-year research project to develop multimodal predictive models that leverage real-world data from sources like circulating tumor DNA sequencing, radiomics, and clinician notes to improve risk stratification and clinical management of non-small cell lung cancer (NSCLC). The goal...
This National Cancer Institute (NCI) Project Grant award under the Cancer Research Manpower program (CFDA 93.398) provides $224,968 to Wake Forest University Health Sciences (WFUHS) to refine and test a cognitive behavioral therapy for insomnia (CBT-I) intervention for lung cancer survivors.
The goal is to enhance the feasibility, acceptability, and symptom management of CBT-I for this high-need population through stakeholder engagement, a 2-arm pilot feasibility trial with 30 participants, and measurement of key patient-reported and objective outcomes. The K99 phase will involve stakeholder interviews and an advisory board to refine the CBT-I intervention. The R00 phase will pilot test the refined CBT-I and evaluate its impact on insomnia, fatigue, pain, anxiety, depression, dyspnea, and cough. This work will support a future large-scale trial to optimize the CBT-I intervention for lung cancer survivors.