This National Cancer Institute (NCI) Project Grant award under the Cancer Research Manpower program (CFDA 93.398) provides $101,458 to the University of Washington to conduct research on quantitatively characterizing tumor heterogeneity using habitat imaging for predicting treatment response and outcomes in triple negative breast cancer (TNBC). The research aims to develop a clinically-translatable methodology that can guide personalized treatment strategies for TNBC patients. This 2-year award will fund retrospective analysis of tumor habitat signatures from pre-treatment multi-parametric MRI to stratify TNBC patients and predict treatment outcome, as well as a prospective study using hybrid PET/MRI for improved patient stratification. The project will be carried out under the mentorship of NCI-funded researchers and clinicians specializing in medical oncology, nuclear medicine, pathology, and radiology at the University of Washington and Fred Hutchinson Cancer Center.
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