Project Grant K99AI187730
Award Date 8/12/25
Completion Date 7/31/26
Dollars Obligated $185K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Philadelphia, PA 19104, USA
Similar Awards
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $769,366 Project Grant under the Allergy and Infectious Diseases Research (CFDA 93.855) program to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania. The grant, effective from February 1, 2025 to January 31, 2030, aims to decipher the ontogeny of CD4+ resident memory T cells that globally seed the skin and protect against cutaneous leishmaniasis. The...
- This federal Project Grant award, valued at $1,826,181.00 and effective from September 1, 2025 to August 31, 2028, was issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research grant program (CFDA 93.846). The grant aims to comprehensively understand the contribution of Langerhans cells, resident cells in the epidermis, to chronic itch associated with various skin and systemic diseases. The research...
- The Project Grant award of $189,376 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) supports research to unravel the interactions between skin microbiota and the immune system that drive early-life commensal tolerance. The research aims to better understand the mechanisms by which conserved microbial signals, specifically those recognized by Toll-like Receptor 2 (TLR2), promote the...
- This Project Grant award of $430,251 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to support fine-resolution genetic mapping of advanced intercross lines of the snail vector Biomphalaria glabrata. The goal is to identify the genomic regions and genes that control the shedding of cercariae, the infectious stage of the Schistosoma mansoni parasite that causes schistosomiasis. The researchers at the University of New...
- This federal Project Grant award of $1,024,897.00 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will fund research at the University of Pennsylvania to dissect the role of innate immune cell responses, particularly inflammatory monocytes and neutrophils, in controlling intestinal and systemic Yersinia infection. The research aims to define how a monocyte-driven TNF-IL-1 signaling circuit mediates control of Yersinia...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $777,360 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University to advance research on lymphatic filariasis (LF) elimination. The project aims to leverage genomic epidemiology to monitor the number of reproductively active adult parasites, differentiate new and established maternal parasite lineages, and understand the drivers of LF resurgence in areas that...
- This federal Project Grant award for $223,500.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to advance scientific understanding of mast cell functions and inflammatory responses. The research will investigate regulatory pathways that limit mast cell activation, with a focus on the role of the ITCH ubiquitin ligase enzyme in controlling inflammation and restoring homeostasis. The project,...
- The University of California, Davis received a $126,738 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) on May 29, 2025. The grant supports research to investigate extramedullary granulopoiesis and immune responses in human skin using a novel skin-on-a-chip model. The project aims to provide mechanistic insight into the migration of hematopoietic stem and progenitor cells into human skin and their role in...
- This Project Grant award of $384,363.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Temple University in Philadelphia, PA. The goal of the research is to study the role of the PELLINO1 (PELI1) protein in regulating antiviral immunity in the skin epidermis, with a focus on herpes simplex virus infections. The researchers will use mouse models and human/mouse cell cultures to define...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855), provides $658,273 to the University of Massachusetts Medical School to study how Herpes Simplex Virus 1 (HSV-1) interacts with and regulates the NLRP1 inflammasome pathway in human skin cells. The key goals are to identify the mechanisms by which HSV-1 activates and inhibits the NLRP1 inflammasome, and to...