Project Grant K99AI184679
Award Date 8/20/25
Completion Date 7/31/27
Dollars Obligated $137K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Baltimore, MD 21201, USA
Similar Awards
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), part of the Allergy and Infectious Diseases Research grant program (CFDA 93.855), provides $463,676 to the University of Maryland, Baltimore for research to enhance the understanding of Fc-mediated effector functions in the context of infectious diseases. The project aims to dissect the mechanisms underpinning Fc-mediated effector functions, with a focus on antibody interactions with a...
- The Project Grant award of $190,315 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will fund a study to characterize the immune response and identify predictive factors for different clinical presentations of Enterovirus D68 (EV-D68) infection. The study aims to: 1) describe the clinical spectrum and identify clinical factors predictive of EV-D68 disease presentations, and 2) characterize the humoral immune response to...
- The University of Maryland, College Park received a $423,803 Project Grant from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to conduct research on defining the STING protein interactions required for rhinovirus replication. The project aims to investigate how the STING protein traffics to viral replication organelles and influences lipid metabolism pathways to promote rhinovirus infection. The award period is from July 15,...
- This Project Grant award of $104,262, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to explore the relationship between genetic variants, transcriptional responses, and tuberculosis (TB) infection outcomes in macrophages derived from genetically diverse mice. The project aims to understand the basis for variability in TB infection outcomes, which may help identify ways to...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $147,486 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University. The purpose of this 20-month grant, with a period of performance from September 2025 to April 2027, is to identify metabolic targets that could reinvigorate exhausted T cells and enhance their function against viruses, bacteria, and tumors. The research aims to elucidate how chronic T cell...
- The federal Project Grant award of $3,436,588.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program. The award supports research to investigate the role of the TLE3 transcription cofactor in regulating the function and persistence of CD8+ T cells during chronic viral infections and cancer. The research aims to molecularly reconstruct the T cell exhaustion process and identify therapeutic...
- The University of Maryland, Baltimore received a $427,625 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to study CD27-mediated immune suppression by hematopoietic stem and progenitor cells (HSPCs), innate immune cells, or non-hematopoietic cells. The research aims to understand how the CD27-CD70 pathway regulates HSPC differentiation and function, and its potential role in modulating allogeneic T cell...
- This federal Project Grant award of $643,718 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand how interferon-regulatory factors (IRFs) and STAT transcription factors remodel the epigenome and chromosome organization of macrophages to reprogram their immune responses. The research aims to: 1) dissect the roles of innate immune IRFs in de novo enhancer formation, 2)...
- This federal Project Grant award, valued at $240,150.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award will investigate the role of the ETS1 proto-oncogene protein in regulating polyomavirus transcription and the viral life cycle. The research aims to elucidate how the polyomavirus large tumor antigen (LT) protein cooperates with the cellular transcription factor ETS1 to...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3,045,291 Project Grant under the Allergy and Infectious Diseases Research (CFDA 93.855) program to The Leland Stanford Junior University. The grant, titled "Molecular Mechanisms of Enterovirus D68 Viral Entry Mediated by the MFSD6 Receptor", aims to study the role of the MFSD6 protein as an entry receptor for Enterovirus D68 (EV-D68) and its importance in disease pathogenesis. The research will focus on...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $136,988 to the University of Maryland, Baltimore to conduct research on the mechanisms by which the transcription factor TFEB regulates autophagy (the cellular degradation process) during infection by Enterovirus D68 (EV-D68). The research aims to enhance understanding of viral manipulation of autophagy and provide insights into the molecular regulation of autophagy. The project period runs from Aug 20, 2025 to Jul 31, 2027.
Generated 10/21/25, 5:58 AM
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $137.0k | 8/20/25 |