The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $143,784 Project Grant (CFDA 93.273 - Alcohol Research Programs) to Louisiana State University Health Sciences Center New Orleans on July 30, 2024. The grant will support research to investigate the effects of adolescent opioid exposure on alcohol-induced hyperalgesia (increased pain sensitivity) in adult mice. The research aims to test the hypothesis that exposure to opioids during adolescence increases the magnitude of...
This $144,362 Project Grant was awarded on July 23, 2024 by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program. The grant supports research to investigate the neural mechanisms underlying the relationship between chronic alcohol exposure and heightened pain sensitivity during alcohol withdrawal. Specifically, the research aims to determine how chronic alcohol exposure impacts the activity of neuropeptide Y...
This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under CFDA Program 93.273 - Alcohol Research Programs, will support research on avoidance learning and pain circuit dysfunction in alcohol use disorders (AUD). The $497,581.76 award, effective September 10, 2024, will enable the principal investigator at Yale University to collect functional MRI data from treatment-seeking AUD patients during a probabilistic learning task involving pain and reward....
This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), provides $159,056 to The Washington University in St. Louis to investigate the role of a novel dynorphinergic central amygdala-nucleus accumbens circuit in driving binge-like alcohol drinking during persistent pain and protracted fentanyl abstinence. The research aims to elucidate the circuit-level mechanisms underlying the co-occurrence of chronic...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a Project Grant under the Alcohol Research Programs (CFDA 93.273) to The Johns Hopkins University in the amount of $807,050 on August 20, 2024. The grant will fund a research project examining the neural circuit effects of chronic alcohol use on cognition and behavior in rodent models. The key objectives are to: 1) Characterize changes in neural activity within the anterior cingulate cortex, orbitofrontal cortex, and...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Illinois. The $293,128 grant, awarded on August 23, 2024, will fund a study examining the neural correlates of alcohol reward in social contexts using a hyperscanning EEG setup. The research aims to evaluate the neural mechanisms underlying the rewarding effects of alcohol in social settings and assess how individual and group-level factors...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $119,253 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of New Mexico Health Sciences Center. The grant will fund research to investigate the impact of third trimester alcohol exposure on sharp-wave ripples, a key neural mechanism for learning and memory, in the hippocampal-retrosplenial cortex circuit. The project will utilize a mouse model, in vivo electrophysiology, and optogenetics...
This Project Grant award, funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) federal grant program, aims to investigate the neural mechanisms driving adaptive stress coping behaviors and subsequent alcohol use. The $498,121.57 award, effective August 15, 2024 through July 31, 2027, will utilize an animal model to explore how dysfunction in the corticolimbic circuitry, specifically the prelimbic cortex and basolateral...
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $537,587 Project Grant under the Alcohol Research Programs (CFDA 93.273) to The University of Texas Southwestern Medical Center to conduct research on the metabolic consequences of liver inflammation on alcohol consumption and alcohol-associated liver disease (ALD). The key objectives are to identify the mechanisms by which the transcription factor IRF3 suppresses the expression and secretion of the metabolic regulator...
This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) program, is providing $1,010,019 to Pennsylvania State University to conduct research on the relationship between the vagus nerve, hypothalamic neurocircuits, and alcohol intake. The key objectives are to: 1) Test the hypothesis that disruptions to the gastric vagus nerve activity will increase alcohol reward and preference, and alter gene...