Project Grant K23NS146764
- The National Institute of Mental Health awarded Cedars-Sinai Medical Center $742,102 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to investigate the neural mechanisms of human working memory through in-vivo single-neuron recordings in patients undergoing treatment for drug-resistant epilepsy. The research deciphers the role of delay-period neural activity in working memory maintenance by recording simultaneously from multiple brain areas. The work...
- Cedars-Sinai Medical Center was awarded a three-year, $934,850 Project Grant from the National Science Foundation Division of Behavioral and Cognitive Sciences under the Social, Behavioral, and Economic Sciences federal grant program (CFDA 47.075). The grant will support research using single-neuron recordings in the human brain to test theories of error monitoring and gain mechanistic insights into how the medial prefrontal cortex enables performance monitoring. Key products include testing...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $438,836 to The Trustees of the Stevens Institute of Technology under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research to develop a unified paradigm using simultaneous multimodal measurement of scalp EEG and intracranial EEG (iEEG) signals to estimate the electrophysiological networks of the whole brain....
- The National Institute of Neurological Disorders and Stroke awarded the University of California, Los Angeles $639,095 on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research on temporal control of neurogenesis termination in developing mammalian brains. The research investigates the molecular mechanisms by which neural stem cells, or radial glia, cease generating neurons shortly after birth—a process...
- The National Institute of Neurological Disorders and Stroke awarded $236,250 to the University of California, Los Angeles on February 3, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate deficits in behavioral time-scale plasticity underlying cognitive representation imprecision and instability in temporal lobe epilepsy. The research examines how behavioral time-scale plasticity—a mechanism for generating...
- The National Institute of Neurological Disorders and Stroke awarded New York University $247,994 on March 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research on ictal onset patterns and responsive neurostimulation outcomes in drug-resistant epilepsy. Dr. Andrew Michalak, an assistant professor of neurology at New York University Grossman School of Medicine, leads the project. The research explores the basic...
- The National Institute of Neurological Disorders and Stroke awarded $198,728 to The Trustees of Columbia University in the City of New York on March 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research quantifying relationships between behavior, neural network activity, and metabolic dysfunction in a genetic mouse model of developmental epileptic encephalopathy. The investigator will measure behavior and...
- The National Institute of Neurological Disorders and Stroke awarded Icahn School of Medicine at Mount Sinai $150,512 on August 5, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into controlling epilepsy symptoms through precisely timed inhibition and circuit editing, focused on temporal lobe epilepsy and cognitive impairments associated with seizure disorders. The research employs closed-loop...
- The National Institute of Neurological Disorders and Stroke awarded the University of Pennsylvania $646,295 on June 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, R01NS148413) to develop quantitative methods for measuring seizure spread and interictal abnormalities on scalp and intracranial electroencephalography (EEG) to improve identification of focal versus diffuse epileptic networks and guide surgical planning for...
- The National Institute of Neurological Disorders and Stroke, an operating division of the National Institutes of Health under the Department of Health and Human Services, awarded $646,706 to Icahn School of Medicine at Mount Sinai on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research to develop and validate magnetic resonance elastography and arterial spin labeling as novel complementary...
The National Institute of Neurological Disorders and Stroke awarded Cedars-Sinai Medical Center $190,321 on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the neurophysiology of cognitive control and its development using single unit intracranial recordings in pediatric patients with epilepsy. The research examines how adaptive behavioral control develops during childhood and is instantiated by prefrontal cortical regions that regulate reflexive and autonomous behavior. The study uses single unit and intracranial electroencephalography (iEEG) recordings from pediatric patients undergoing intracranial electrode implantation for seizure onset zone mapping. Investigators will employ an action modification task to quantitatively elicit cognitive control and combine single unit recordings from the dorsal anterior cingulate cortex and presupplementary motor area with iEEG recordings from the inferior frontal gyrus to identify neurophysiological dynamics underlying behavioral performance within each patient. Data from patients at distinct developmental stages will characterize how neurophysiological correlates of cognitive control change during brain maturation. The project is designed as a mentored grant to facilitate the principal investigator's transition to scientific independence. Performance occurs in West Hollywood, California, with a period of performance through May 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $190.3k | 8/11/26 |