Project Grant K23MH137567

Award Date 5/1/25
Completion Date 4/30/29
Dollars Obligated $177K
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
Virginia, USA
Similar Awards
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is providing $522,737.71 to the University of California, San Diego (UCSD) to conduct a multi-year research project titled "Towards an Etiological Model of Adolescent Eating Disorders through Neuroimaging, Genetics, and Behavior." The key objectives of this project are to: Identify behavioral and neuroimaging-derived correlates of eating disorders...
This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA Program 93.242 - Mental Health Research Grants aims to study avoidance learning in individuals with eating disorders such as anorexia nervosa (AN) and bulimia nervosa (BN). The $874,625 award to the University of California, San Diego (UCSD) will support a 2-year study examining instrumental learning strategies to avoid harm, and how this relates to eating disorder symptoms and associated neural mechanisms....
This $148,142 federal Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports a research project conducted by Virginia Commonwealth University to examine neurodevelopmental trajectories of the hippocampus as a mechanism linking child maltreatment to adverse mental health outcomes in adolescents. The project aims to: 1) identify trajectories in adolescent hippocampal development as a function of different child...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) totaling $1,611,022 provides funding to the University of Pittsburgh to conduct longitudinal research on adolescent brain maturation and psychopathology. The key objectives are to: 1) Examine neuropil growth/contraction using 3D whole-brain phosphorus magnetic resonance spectroscopy, 2) Elucidate alterations in multiple brain network modalities using a...
This federal Project Grant award, valued at $941,616.00 and provided by the National Institute of Mental Health (NIMH) under CFDA Program 93.242 - Mental Health Research Grants, supports research to investigate the relationship between food cue exposure, food craving, and binge eating behaviors, and how these relationships are influenced by attention and memory processes. The key objectives are to use ecological momentary assessment and electroencephalography to examine how food cue exposure...
This $248,998 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund research into the neural circuit mechanisms underlying motivation. The principal investigator, a newly appointed Assistant Professor at Dartmouth College, will use in vivo calcium imaging and optogenetic stimulation to study the role of GABA/glutamate co-releasing neurons in the ventral tegmental area (VTA) and their projections to the...
This federal Project Grant award, totaling $1,648,532, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award will fund a multi-year research study at the University of North Carolina at Chapel Hill to characterize the role of acute stress response mechanisms, both physiological and neural, in the severity and trajectory of anhedonia (reduced ability to experience pleasure) during adolescence. The study will utilize...
This $792,441 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund a study investigating the dynamic neural and physiological stress responses of female adolescents at high and low familial risk for depression. The study aims to track changes in default mode network and central executive network connectivity, along with psychophysiological markers like heart rate, heart rate variability, skin...
This federal Project Grant award of $1,682,938.00, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), aims to optimize an automated chatbot to deliver efficient and scalable treatment for eating disorders (EDs). The key products and services to be delivered include: Building on prior research, the project will test four candidate ED treatment components (targeting overevaluation of weight/shape, dietary restraint, emotion...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $811,404 to support research on the neural circuit mechanisms underlying anticipatory anhedonia (inability to experience pleasure) in schizophrenia. The funded research aims to utilize a computational psychiatry approach to dissect the neural circuitry involved in altered reward anticipation processes, which may contribute to anhedonia...

This federal Project Grant award for $176,960 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support a research study by Virginia Commonwealth University (VCU) on the development of exploration strategies and associated neural circuitry in adolescents with bulimia nervosa (BN).

The study will use an accelerated longitudinal design to examine shifts in exploration strategies and neural correlates over time in cohorts of early, middle, and late adolescent girls with BN compared to matched controls. Participants will complete a bandit task during fMRI scanning to assess exploration strategies, with follow-ups at 1 and 2 years to track developmental changes. The goal is to elucidate the neurocomputational basis of impulsivity in adolescent BN to inform more targeted interventions. The award will also provide the principal investigator mentorship and training in neurodevelopmental methods, computational modeling, and translational reward processing frameworks to support their transition to research independence.

Generated 5/13/25, 2:17 AM