Project Grant K23HL186449
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Leland Stanford Junior University a $410,449 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) beginning August 1, 2025, with a completion date of July 31, 2027. This grant supports the development of novel synthetic biology strategies to enhance cell-based therapies for peripheral arterial disease (PAD), a condition affecting over 8 million Americans. The research will...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the Research Institute at Nationwide Children's Hospital a $1,326,945 Project Grant on September 10, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and validate an advanced molecular imaging approach for assessing peripheral artery disease (PAD). The core deliverable is a dual-phase positron emission tomography/computed tomography (PET/CT) imaging paradigm using...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded $246,000 to the University of California, San Francisco (UCSF) under the Cardiovascular Diseases Research program (CFDA 93.837) on July 6, 2026, with a completion date of June 30, 2028. This R21 resubmission leverages UCSF's existing Ventricular Tachycardia (VT) Database—a comprehensive, expertly annotated dataset encompassing 5,679 consecutive intensive care unit (ICU) patients with 572,574 hours...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $128,097 Project Grant to the University of California Irvine effective September 30, 2025, through March 29, 2029, under the Cardiovascular Diseases Research program (CFDA 93.837). The project deliverables focus on developing and validating physiologically relevant intermittent hypoxia (IH) protocols using endothelial cells and patient tissue samples, with results to be applied to an innovative...
- Federal Grant Award Summary The University of California, San Francisco (UCSF) received a $722,299 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective August 1, 2025 through July 31, 2030. This award funds a research initiative applying deep learning models to quantify aortic valve measurements in 100,000 UK Biobank participants to identify shared genetic and epidemiological factors underlying normal...
- Federal Project Grant Award Summary Arizona State University received a $252,676 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 15, 2025, with completion targeted for August 31, 2027. The award funds development and evaluation of the Computer Aided Exercise Stress ECG Reader (CAESAR), an artificial intelligence-driven diagnostic tool designed to improve the accuracy of exercise stress...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded University of California Irvine $1.207 million under the Cardiovascular Diseases Research program (CFDA 93.837) on August 15, 2025, to develop an integrated multimodal intravascular imaging system for diagnosing and characterizing vulnerable atherosclerotic plaques. The system combines optical coherence tomography (OCT), intravascular ultrasound (IVUS), photoacoustic tomography (PAT), and...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Kaiser Foundation Hospitals $3.92 million through the Cardiovascular Diseases Research program (CFDA 93.837) on September 27, 2025, for the HIDDEN-ASCVD (Harnessing Artificial Intelligence and Deep Learning to Determine a Coronary Artery Calcium Estimate in Patients with No History of Atherosclerotic Cardiovascular Disease) Study, with completion scheduled for August 31, 2029. The project leverages deep...
- Federal Project Grant Summary Award Details: Pulseimaging.ai, LLC received $304,415 in federal funding under the National Heart, Lung, and Blood Institute's (NHLBI) Cardiovascular Diseases Research program (CFDA 93.837). The award was obligated on August 15, 2025, with a completion date of August 14, 2027. Products and Services: The awardee will develop an artificial intelligence-enabled software solution designed to predict future cardiovascular events from screening CT calcium score (CTCS)...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded University of California, Los Angeles $1,574,590 under the Cardiovascular Diseases Research program (CFDA 93.837) on July 15, 2026, with a completion date of March 31, 2028. This Project Grant funds basic and translational research to elucidate the role of alternative polyadenylation (APA) in cardiovascular disease and lipid metabolism. The research integrates computational, molecular, cellular, and...
The National Heart, Lung, and Blood Institute (NHLBI) awarded $177,814 to the University of California, San Diego on July 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and validate smartphone-based digital biomarkers for detecting peripheral artery disease (PAD) and coronary artery disease (CAD). The project, scheduled for completion by June 30, 2031, leverages photoplethysmography (PPG) technology integrated into mobile devices and wearables to create a scalable, non-invasive diagnostic solution that addresses critical gaps in early vascular disease detection. This approach aligns with NHLBI's mission to reduce cardiovascular disease burden through innovative diagnostic technologies suitable for deployment at clinical scale. The award supports three primary aims: validation of the PAD digital biomarker against the gold-standard ankle-brachial index (ABI) in a prospective study of 349 participants; assessment of the biomarker's diagnostic performance for detecting coronary atherosclerosis against the gold-standard coronary artery calcium (CAC) Agatston score in a prospective study of 392 participants; and evaluation of usability, feasibility, and acceptability of the smartphone-based PPG application in clinical settings using mixed-methods research grounded in human-centered design and implementation science frameworks. The project aims to overcome limitations of conventional diagnostic methods that require specialized equipment and trained personnel, thereby enabling broader access to early vascular disease detection.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $177.8k | 7/10/26 |