Project Grant K23HL179415
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a $169,352 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective June 16, 2025, with completion targeted for December 21, 2027. This award funds research aimed at characterizing NRAC (Nutritionally Regulated Adipose and Cardiac-Enriched Gene), a novel microprotein involved in lipid droplet biogenesis and...
- Federal Grant Award Summary Cincinnati Children's Hospital Medical Center received a $731,130 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 19, 2025, with completion targeted for June 30, 2030. The award supports a multi-site, two-stage Sequential Multiple Assignment Randomized Trial (SMART) designed to evaluate the effectiveness of an adaptive mobile health (mHealth) intervention for...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Boston Children's Hospital a Project Grant totaling $117,525 on July 7, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837). The three-year project, extending through June 30, 2028, supports fundamental research investigating cellular adaptation mechanisms in response to one-carbon (1C) metabolism perturbation, with particular focus on erythroid cell responses to folate deprivation. The...
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a $511,987 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective August 27, 2025, with a completion date of May 31, 2029. The award funds a comparative mechanistic study of lamin-related cardiomyopathy (LMNA-related dilated cardiomyopathy), specifically investigating two prevailing hypotheses regarding...
- Federal Grant Award Summary Cincinnati Children's Hospital Medical Center received a $1,429,215 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective June 1, 2025, through March 31, 2029. The award supports basic and translational research investigating MEOX2 as a critical regulator of alveolar fibroblast function and its role in lung development and disease. The research aims to elucidate molecular...
- Federal Grant Award Summary Cincinnati Children's Hospital Medical Center received a $727,575 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective August 15, 2025, with completion targeted for May 31, 2030. The project will investigate the cellular mechanisms and clinical impact of the genetic variant rs7512462 within the SLC26A9 gene on individual patient responses to cystic fibrosis (CF)...
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a $249,000 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 25, 2025, with completion targeted for July 31, 2028. The award supports research investigating the molecular mechanisms linking the transcription factor PITX2 (Pituitary Homeobox 2) to atrial fibrillation (AF) risk through...
- Federal Grant Award Summary Cincinnati Children's Hospital Medical Center received a $456,914 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) effective September 1, 2025, through August 31, 2027. The award supports research to evaluate electronic health record (EHR)-based prediction of obesity in infants using World Health Organization (WHO) weight velocity standards and...
- Federal Project Grant Award Summary Cincinnati Children's Hospital Medical Center received a $120,375 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective April 15, 2026, with completion anticipated by January 31, 2028. The award supports the development of FLUME (Fetal Lung Multiomics Exploration), a human fetal lung multiomics cell atlas with computational models designed to predict fetal...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded Children's Mercy Hospital a $376,146 Project Grant (CFDA 93.837—Cardiovascular Diseases Research program) effective May 1, 2025, through April 30, 2030, to support a five-year career development initiative (K23 mechanism) under the direction of Dr. Kathryn Kyler. The primary product of this award is the development of Dr. Kyler as an independent investigator in pharmacokinetic (PK) modeling and...
Cincinnati Children's Hospital Medical Center received a $191,636 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded April 1, 2026, with a completion date of March 31, 2031. This award funds a longitudinal research study examining the relationships among food insecurity, loss of control eating, and cardiometabolic health risk in Hispanic/Latino adolescents. The research involves quantitative data collection at baseline, 3-month, and 6-month intervals, including fasting laboratory assessments of cardiometabolic health indicators at baseline and 6-month follow-up visits, combined with qualitative interviews of caregivers regarding intergenerational factors affecting eating behavior and community food access experiences. The grant supports intervention development activities utilizing the Obesity-Related Behavioral Intervention Trials (ORBIT) Phase IA and IB methodology, which includes defining modifiable intervention targets, adapting evidence-based intervention components tailored to participant needs, and refining intervention content through focus group feedback. Additionally, the award provides career development support for the Principal Investigator, Dr. Bejarano, through mentorship in community-engaged research strategies with Hispanic/Latino populations, ORBIT intervention development, clinical trials methodology, and prevention science. Upon completion, these research outputs will inform the development of a preventive intervention designed to address disordered eating and cardiometabolic health risk in this high-risk population.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $191.6k | 4/2/26 |