Project Grant K23HL175246
Award Date 9/25/25
Completion Date 7/31/30
Dollars Obligated $186K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Nashville, TN 37203, USA
Similar Awards
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $874,997 to Vanderbilt University Medical Center (VUMC) to conduct a randomized trial evaluating personalized oxygen therapy for critically ill, mechanically ventilated adults. The project aims to develop and validate a statistical model that can predict the optimal oxygen saturation target for individual patients to reduce mortality, compared to usual care....
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $185,720.00 to Vanderbilt University Medical Center (VUMC) to conduct a randomized clinical trial investigating the use of sedation-only versus sedation with neuromuscular blockade for emergency tracheal intubation of critically ill adults. The primary aim is to evaluate whether the sedation-only approach can prevent hypoxemia, which more than doubles the...
- This federal Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $748,970 in funding to The Trustees of the University of Pennsylvania to conduct research aimed at better understanding the implementation of evidence-based treatments for mechanically ventilated patients in intensive care units (ICUs). The key research objectives are to: 1) quantify the penetration over time of four evidence-based treatments (sedation...
- This federal Project Grant award, valued at $272,226.00, was granted by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837). The project aims to determine how clinician and scheduling characteristics impact patient outcomes, and explore the moderating effect of patient characteristics on these relationships, for mechanically ventilated adults in intensive care units. The project will conduct a novel secondary analysis utilizing a unique...
- The University of Texas Southwestern Medical Center received a $685,724 project grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to conduct a multi-center observational study on the association between ventilation and cardiac arrest outcomes. The study will leverage data from a large clinical trial database to analyze ventilation metrics using a machine learning algorithm developed to measure ventilation during continuous chest...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $761,599.00 to Trustees of Boston University, doing business as Boston University Medical Campus, to conduct research on quantifying uncertainty to inform time-limited trials of invasive mechanical ventilation. The research aims to fill critical knowledge gaps around clinicians' ability to recognize prognostic uncertainty, optimal durations for time-limited trials,...
- This federal Project Grant award of $159,624.00 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research at Vanderbilt University Medical Center (VUMC) to investigate the role of hypoxia-inducible factor (HIF) in promoting alveolar regeneration and functional lung repair for patients with idiopathic pulmonary fibrosis (IPF) and other chronic lung diseases. The research aims to explore how modulating upstream disease mechanisms,...
- This Project Grant award of $178,846.00 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to optimize ventilator management for patients with acute respiratory distress syndrome (ARDS) who require extracorporeal membrane oxygenation (ECMO) support. The primary goal is to determine if personalized positive end-expiratory pressure (PEEP) settings guided by esophageal manometry can reduce ventilator-induced lung injury (VILI), as measured by...
- This federal Project Grant award of $430,606 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to create a new Pediatric Cardiorespiratory Research Training Program at Vanderbilt University Medical Center (VUMC). The goal is to provide 2-3 years of highly rigorous research training for pediatrics fellows and PhD scientists to facilitate their transition to tenure-track faculty positions as clinician-scientists. The program will support up to 2...
- This Project Grant award of $807,067.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support a study to pioneer the quantitative documentation of human respiratory kinematic profiles. The study aims to address a critical gap in contemporary physiological monitoring - the inability to quantify labored breathing, which contains vital prognostic information not captured by conventional monitoring. Building on a recent innovation called ARK...