Project Grant K23HL175238
- The University of Alabama at Birmingham (UAB) received a $222,750 Project Grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to develop a clinical decision support questionnaire to identify barriers to blood pressure control. The project aims to address the high rates of uncontrolled hypertension in the U.S., which is a leading cause of morbidity, mortality, and substantial healthcare costs. The award, with a performance period from July...
- The University of Alabama at Birmingham (UAB) received a $637,732 project grant from the National Heart, Lung, and Blood Institute's Cardiovascular Diseases Research program (CFDA 93.837) to conduct research on improving the cardiac microenvironment as a novel strategy against diabetic ischemic heart failure. The project aims to leverage insights from cellular secretome research to transform treatment strategies for diabetic ischemic heart failure. Specifically, the research will investigate how...
- The University of Alabama at Birmingham (UAB) was awarded a $663,730 Project Grant from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) on August 20, 2025. The goal of this grant is to investigate the role of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in regulating metabolic reprogramming of lung macrophages and its impact on the progression of asbestos-induced lung fibrosis. Key objectives include determining if metabolic...
- The federal Project Grant award of $535,556.00 was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of Alabama at Birmingham (UAB). The funding will support a research project to investigate the role of a novel histone modification, H3T32 O-GlcNAc, in endothelial cell dysfunction and atherosclerosis. The 5-year project aims to elucidate the epigenetic features of this histone modification under...
- The University of Alabama at Birmingham (UAB) was awarded a $539,342 Project Grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to conduct research on the circadian mechanisms governing cardiac growth. The project aims to investigate how the cardiomyocyte circadian clock regulates cardiac processes, particularly the branched chain amino acid catabolism and mTOR activation during the active and sleep periods. This research seeks to advance...
- This federal Project Grant award, valued at $162,703.00 and granted by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research), aims to determine whether streamlined, standardized blood pressure (BP) measurement protocols can be implemented in primary care settings. The project builds on the Alabama Cardiovascular Cooperative's Heart Health Improvement Project and seeks to improve the accuracy and efficiency of BP measurements to inform treatment decisions...
- This Project Grant award of $234,750.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to examine the immunological mechanisms that initiate and orchestrate the development of anti-factor VIII alloantibodies, known as inhibitors, in patients with severe hemophilia A. The research is being conducted by Emory University and seeks to identify key immune pathways and risk factors that predict the likelihood of inhibitor development, with the goal...
- This $601,677 Project Grant award from the National Heart, Lung, and Blood Institute's Cardiovascular Diseases Research program (CFDA 93.837) will support a multi-scale study of the mechanisms underlying vaccine-induced immune thrombotic thrombocytopenia (VITT). The University of Massachusetts will conduct experimental and modeling research to characterize the formation of platelet-activating immune complexes and thrombus development triggered by adenoviral-vectored vaccines. The research aims...
- The University of Alabama at Birmingham (UAB) was awarded a $1,263,750 Project Grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) on September 5, 2025. The grant supports the development of AI-enabled tools for data harmonization and leveraging existing data to facilitate more robust research in health promotion and secondary condition prevention (HP/SCP) for...
- The University of Cincinnati, through its Sponsored Research Services Division, was awarded a $156,276 project grant by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct research on "Hematopoietic Cells and Chemokine Regulation in Abdominal Aortic Aneurysm Associated Thrombosis". The project, with a performance period from August 1, 2025 to June 30, 2027, aims to investigate the role of platelet activation and...
The University of Alabama at Birmingham (UAB) was awarded a $186,153 federal Project Grant from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) on September 16, 2025. The grant aims to enhance representation in clinical trials and investigate sociodemographic and clinical factors associated with secondary anticoagulation use and outcomes in children with venous thromboembolism (VTE). The project will systematically analyze VTE data from a multicenter prospective cohort study to better understand factors that contribute to VTE recurrence in pediatric patients, including the impact of social determinants of health. This research seeks to address critical knowledge gaps and develop improved VTE prevention strategies for this population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $186.2k | 9/17/25 |