This $673,581 Project Grant was awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) to study asthma care disparities between Latino and non-Hispanic white adults. The grantee, Ochin, Inc., a nonprofit health IT collaborative in Portland, Oregon, will leverage a unique dataset to assess these disparities and identify the individual- and community-level social determinants of health that most significantly impact...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $164,453 Project Grant (CFDA 93.837 - Cardiovascular Diseases Research) to the Arkansas Children's Research Institute (ACRI) on September 15, 2024. The grant will fund a 4-year research project titled "Multifactorial Asthma Determinants in Underresourced Pediatric Populations." The project aims to investigate disparities in pediatric asthma prevalence and morbidity, particularly among racial/ethnic minority and rural,...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $797,130 to The Children's Hospital of Philadelphia (CHOP) from September 2024 to June 2028. The project aims to implement and evaluate the real-world effectiveness of "single maintenance and reliever therapy" (SMART) for managing moderate-to-severe childhood asthma in a predominantly Black pediatric population. The study uses a...
The Project Grant award K23HL163253, totaling $178,783, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The award will support Dr. Pappalardo's research to understand barriers and develop targeted implementation strategies for school-based stock inhaler programs, with the goal of improving asthma management and reducing health disparities. The grant will fund a community-engaged, implementation science...
This $177,403 Project Grant was awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research (CFDA 93.837) program. The funding supports research to disentangle the heterogeneity of asthma, identify distinct asthma endotypes, and investigate biological mechanisms underlying established risk factors. The project will utilize multi-omics data from three cohorts of asthmatic children to analyze the interplay between genetic, epigenetic, and metabolomic...
This $274,392 Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports a study to better understand the relationship between social determinants of health (SDOH) and asthma outcomes among Black and Latinx adults with moderate-to-severe asthma. The study aims to: Determine if Black and Latinx adults have unique SDOH exposomes (a set of SDOH exposures) that associate with worse asthma morbidity. It will...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $844,386 to support research on the genetic landscape of childhood interstitial and diffuse lung diseases (CHILD). The key objectives are to: 1) Define molecular profiles of 300 CHILD lung biopsy samples to identify patient clusters with similar underlying causes, 2) Analyze whole exome sequence data from 400 children with...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $288,986 to Biotherapeutics, Inc., a biotechnology company in Blacksburg, VA. The grant supports the development of a novel oral immunoregulatory therapeutic for the treatment of asthma. The key objectives are to: 1) Determine the safety profile and pharmacokinetics of the new therapeutic in rats, and 2) Characterize the therapeutic...
This federal Project Grant award from the National Institute of Nursing Research (NINR) under CFDA 93.361 - Nursing Research, will support the development and evaluation of IMAAP, an interactive mobile asthma action plan. The $441,375 award, effective July 17, 2024 through May 31, 2026, aims to create an innovative technology that leverages objective lung function assessment, symptom reporting, and personalized treatment recommendations to empower adolescents, particularly those from...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, provides $863,328 to Aquillius Corp to develop a wearable graphene respiratory sensor for early detection and continuous monitoring of asthma. The goal is to create a cost-effective, robust device suitable for all ages that can measure pulmonary functions in real-time to improve patient monitoring, treatment, and diagnosis of asthma. The Phase I...