Project Grant K23HD117039
- The U.S. Department of Health and Human Services, National Institutes of Health (NIH) awarded a $1,017,548 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the University of North Carolina at Chapel Hill. The grant, titled "HOME GROWN: A FAMILY-BASED LIFESTYLE INTERVENTION TO SUPPORT HEALTHY DEVELOPMENT OF YOUNG CHILDREN WITH DOWN SYNDROME," will fund a 2-phase study to evaluate the feasibility (R61 phase) and efficacy (R33 phase) of a tailored healthy...
- This Project Grant award from the Department of Health and Human Services National Institutes of Health (CFDA 93.310 Trans-NIH Research Support) provides $446,096 to the University of Illinois to develop and implement community-based participatory health research with young adults with Down syndrome. The project aims to reflect the perspectives and lived experiences of adults with Down syndrome, including those from underserved and underrepresented communities, to reduce health disparities and...
- The University of California, Davis received a $250,000 Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to conduct a 3-year longitudinal investigation of expressive communication (EC) development in 180 children with Down syndrome from 18 to 54 months of age. The project will use deep-phenotyping and dense-sampling methods, both in-person and via telehealth monitoring, to enhance understanding of the variability, nature, and...
- This $116,685 federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under CFDA Program 93.865 - Child Health and Human Development Extramural Research will support research to understand the needs of children with Down syndrome who have survived leukemia and their families during the reintegration process. The award recipient, the University of Wisconsin System, will conduct a convergent mixed methods study to examine the...
- This federal Project Grant award for $152,816.00, provided by the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research), aims to investigate the link between Down's syndrome (trisomy 21) and placentation defects. The research will focus on: Identifying transcriptional differences in implantation-stage trophoblasts between trisomy 21 and euploid induced pluripotent stem cell lines through RNA-sequencing. Assessing the...
- The federal Cooperative Agreement award U01HD116463, titled "The Infant Down Syndrome Brain and Behavior Study", is funded by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The $2,927,457 award will support a longitudinal study to collect multimodal neuroimaging, cognitive/behavioral data, and social communication measures in a cohort of 100 infants with Down syndrome and 50 typically developing controls. The study aims to...
- This $5.2 million project grant from the Department of Health and Human Services National Institutes of Health Office of the Director, under the Trans-NIH Research Support program, will fund research at the University of Colorado Denver to study neurovascular dysfunction in individuals with Down syndrome revealed by traumatic brain injury. Over three years, the collaborative multi-principal investigator team will establish how trisomy 21-related cellular defects and candidate genes exacerbate...
- This $2,598,199 Cooperative Agreement, awarded by the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), will support a multi-center, multi-disciplinary research project titled "Advancing the Lives & Health of Youth and Young Adults with Down Syndrome (ALLY-DS)." The project aims to establish a diverse cohort of individuals with Down syndrome for comprehensive longitudinal phenotyping, including multi-omics data...
- This $131,166 Project Grant awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to understand the economics and impacts of extending special education services for individuals with developmental disabilities, including Down syndrome. The principal investigator will apply causal inference methods to large administrative datasets to...
- This federal Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) is providing $661,575 to Children's Hospital Los Angeles to conduct a 5-year study on Down Syndrome Regression Disorder (DSRD). The principal investigator, Dr. Jonathan D. Santoro, is an international expert on DSRD, a neuropsychiatric condition in individuals with Down Syndrome that causes severe...
The National Institute of Child Health and Human Development (NICHD) awarded a $163,813 Project Grant to the University of Colorado-Denver (UCD) for the project "Improving Health Care Communication and Engagement for Adults with Down Syndrome." The 5-year grant, starting on September 3, 2025, aims to address health disparities experienced by individuals with Down syndrome by developing and piloting a patient-and-supporter-driven communication tool tailored for adults with Down syndrome. The project will involve analyzing communication quality in primary care encounters, adapting an existing communication tool to meet the needs of adults with Down syndrome, and conducting a feasibility trial of the adapted tool with clinicians, adults with Down syndrome, and their supporters. The grant is funded under the NICHD's Child Health and Human Development Extramural Research program (CFDA 93.865), which supports research to advance scientific understanding of human development, reproductive health, and child/adolescent wellness.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $163.8k | 9/3/25 |