The National Eye Institute (NEI) of the National Institutes of Health awarded a $286,534 Project Grant under the Vision Research program (CFDA 93.867) to Regents of the University of Michigan, to be performed at the University of Michigan in Ann Arbor. The grant runs from January 1, 2025 through December 31, 2028 and aims to investigate longitudinal changes in the gut microbiota and metabolome in patients with non-infectious uveitis, an eye condition characterized by intraocular inflammation. The research will compare the gut microbiota and metabolomic profiles between uveitis patients and healthy controls, and assess whether changes in the gut microbiome correlate with disease activity and treatment response. This work is expected to lead to an improved understanding of the gut-eye axis in uveitis and inform precision medicine approaches for this ocular inflammatory condition.
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