This $149,857 Project Grant, awarded on July 7, 2025 by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to investigate the role of inhaled particulate matter (PM) in exacerbating pulmonary vascular remodeling associated with pulmonary hypertension (PH). The research aims to define population-level associations between aryl hydrocarbon receptor (AhR) agonism, plasma metabolites, and PH severity; determine if...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $343,146 to conduct research on the mortality risk associated with air pollution exposure among U.S. veterans with chronic respiratory diseases. The award to the Regents of the University of Minnesota aims to: 1) estimate the mortality risk in chronic respiratory disease populations attributed to daily fine particulate matter...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $526,627 to the Regents of the University of Michigan to investigate the mechanisms driving fibrosis in silicosis and asbestosis. The research aims to define specific cell state changes in alveolar epithelial cells that lead to impaired regeneration and promote non-resolving fibrosis in response to silica and asbestos...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program provides $676,077 to Colorado State University (CSU) to study the impacts of fine particulate matter (PM2.5) air pollution on cardiovascular and respiratory health outcomes. The key products and services being delivered under this award include: Deploying a national network to measure the oxidative potential of PM2.5 samples, which...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, is supporting research to investigate the genetic mechanisms underlying maladaptive respiratory responses to air pollution, specifically ozone (O3) exposure. The $671,165 award, spanning January 1, 2025 to October 31, 2029, will enable researchers at the University of North Carolina at Chapel Hill to: Profile the transcriptomes and...
This Project Grant award of $5,715,866 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to develop novel, transformative therapies that substantially reduce the burden of morbidity and mortality from progressive pulmonary fibrosis (PF). The multi-year program, which began in September 2024, focuses on investigating the transcriptomic, genetic, epigenetic, metabolic, and environmental signatures that contribute to the initiation and early...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $893,525 to The Johns Hopkins University to implement and evaluate a multi-component intervention to protect lung health in Nepal. The 5-year project aims to reduce environmental risk factors like tobacco smoking and air pollution, as well as infectious risks, through community health worker-delivered education, household...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $702,364 to Yale University to conduct a nationwide analysis investigating the health impacts of fine particulate matter (PM2.5) exposure from different source sectors and fuel types. The key objectives are to: Estimate PM2.5 exposure by chemical components, source sectors, and fuel types across the continental U.S. from...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) Federal Grant Program, provides $1,054,600.00 to the Regents of the University of Michigan to study the mechanisms underlying impaired regeneration of alveolar epithelial cells and progressive fibrosis in silicosis and asbestosis. The research aims to define distinct subsets of transitional alveolar epithelial cells, elucidate signaling pathways that prevent...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $419,011 to Emory University to develop innovative dimensionality reduction techniques for assessing the joint health effects of air pollution mixtures. The research aims to advance causal modeling approaches that preserve the relationships between air pollutants and health outcomes, in order to provide more accurate assessments of the public...