This $195,156 five-year federal Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) supports the development and evaluation of a novel, culturally tailored, family-based digital intervention called FamilyBOND (FAMB). FAMB aims to prevent increases in substance misuse among urban Black mid-adolescents with early substance use. The project includes 1) developing FAMB and assessing its usability among Black adolescents and parents, and 2) evaluating the feasibility and effect size of FAMB in lowering adolescent intention to misuse substances, improving parental self-efficacy regarding substance misuse communication, and enhancing parent-adolescent communication about substance misuse. This grant will provide the Principal Investigator critical training in community-engaged research, developing family-based digital substance misuse prevention interventions, implementation science, and conducting randomized controlled trials to address substance use challenges among Black adolescents.