Project Grant K23AI189218
- This Project Grant award, totaling $2,314,470 and provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to explore the impact of gender-affirming hormone therapy on HIV viral dynamics and immune responses in transgender women. The project leverages two unique cohorts of transgender women - one cross-sectional cohort of 120 participants divided by HIV serostatus and hormone exposure, and a...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $801,363 Project Grant under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) to the New York Blood Center, Inc. to study the immune and behavioral responses of transgender women to seasonal COVID-19 vaccines. The goal is to understand how exogenous sex hormones from gender-affirming hormone therapy impact immune responses and vaccination outcomes in this population, which could help...
- This Project Grant award of $533,707 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research at Tufts University School of Medicine to investigate how human papillomavirus (HPV) manipulates the Hippo signaling pathway to maintain persistent infection in basal epithelial cells. The research aims to elucidate the role of the HPV E7 protein in disrupting the balance between proliferation and...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $6,319,992 to Tufts University School of Medicine to conduct research on how human papillomavirus (HPV) proteins reprogram host cell signaling pathways. The research aims to determine the essential cellular targets of the HPV E7 protein, specifically the RB1 and PTPN14 tumor suppressors, and how their inactivation enables HPV to drive...
- The Johns Hopkins University was awarded a $672,248 Project Grant from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research) to study sex-specific features of the HIV reservoir and immune responses across the female reproductive lifespan in a cohort of Ugandans living with HIV. The 5-year project, which began on September 15, 2025, aims to: 1) analyze the impact of pregnancy on HIV reservoir and immunity, 2) assess HIV reservoir and...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $2,461,651.00 to the University of Texas Health Science Center at Houston to investigate the impact of estrogen on IgG glycosylation and its effects on immune function and inflammation in people with HIV. The research aims to determine if estrogen can reverse the HIV-associated loss of IgG galactose, which has been linked to reduced antiviral...
- This Project Grant award of $131,166 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports a research project to identify protective T cell epitopes for an HPV therapeutic vaccine. The project aims to develop novel strategies for enhancing T cell-mediated immunity against HPV infection, which is critical for eliminating pathogens post-infection, an area where existing HPV vaccines...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), provides $439,088 to The General Hospital Corporation (doing business as Massachusetts General Hospital) over a 2-year period from Jul 8, 2025 to Jul 7, 2027. The purpose of the grant is to mechanistically define how sex differences in hormones and circulating cytokines, specifically the cytokine APRIL, modulate B...
- This federal Project Grant award, titled "Aligning HIV Services with Gender Diverse Community Priorities Through Person-Centered Care: A Mixed Methods Study in India", is funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The $146,922 award will support a mixed-methods study to explore how a person-centered care model can improve HIV testing engagement and service access for transgender and gender diverse (TGD)...
- This federal Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $170,411 in funding from August 8, 2025 to July 31, 2030 to support mentorship and training of early career investigators in translational virological research focused on HIV persistence, therapeutic interventions, and drug resistance. The grant recipient, Brigham & Women's Hospital Inc., will leverage...
This $140,740 federal Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support a study on the role of gender-affirming hormone therapy in anal human papilloma virus (HPV) persistence and immunity among transgender women with and without HIV. The researchers will conduct a secondary analysis of samples from transgender women and cisgender men who have sex with men to assess the effect of gender-affirming hormone therapy on systemic HPV16 immunity and the proportion of peripheral HPV-specific T-cells and antibodies. This research aims to address a critical gap in understanding the impact of gender-affirming hormones on HPV immunity and persistence, which could inform the development of novel HPV immunotherapies targeting anal dysplasia in the transgender women population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $140.7k | 9/12/25 |