Project Grant K23AG090691
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $6,742,946 Project Grant to the University of Michigan to evaluate the effects of personalized brain stimulation as a potential treatment for individuals with posterior cortical atrophy (PCA), which is often caused by Alzheimer's disease. The 4-year study will use functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) scans to identify and target the...
- This Project Grant award of $1,006,653 from the National Institute on Aging (CFDA 93.866 - Aging Research) to Posit Science Corp. supports the "IMPROVING NEUROLOGICAL HEALTH WITH ACETYLCHOLINE VIA NEUROPLASTICITY-BASED COMPUTERIZED EXERCISE IN MILD COGNITIVE IMPAIRMENT (INHANCE-MCI)" program. The project aims to deploy a computerized cognitive training program that integrates validated exercises to potentially reduce the long-term risk of dementia onset in individuals with mild...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $344,164 project grant to Northwestern University to develop "M4: Modules on Advanced Methodology When Modeling Multinational Data." The primary objectives are to: 1) create a training program in large-scale data analysis for the next generation of researchers, 2) instruct trainees on protective behavioral and social factors related to Alzheimer's disease and related dementias...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $167,940 project grant to The Children's Hospital Corporation (Boston Children's Hospital) to elucidate the neuronal mechanisms underlying cognitive resilience to Alzheimer's disease. The project, awarded on August 15, 2025, aims to (1) determine if the MEF2 transcription factors mediate survival of specific neuronal subtypes vulnerable to Alzheimer's pathology, (2) assess whether...
- The National Institute on Aging (NIA) awarded a $1,010,368 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Koronis Biomedical Technologies Corp. (KBT) to develop and validate an interactive gaming platform to facilitate cognitive interventions for individuals living with mild cognitive impairment (MCI) or Alzheimer's disease and related dementias (AD/ADRD). The goal is to create an in-home cognition training system that provides evidence-based cognitive activities...
- This federal Project Grant award of $223,813 from the National Institute on Aging (CFDA 93.866 Aging Research) supports a 2-year cross-sectional and longitudinal study in Nigeria to investigate the use of plasma biomarkers, social determinants of health, and lifestyle factors in classifying and predicting mild cognitive impairment and Alzheimer's disease. The study will enroll 264 participants across three cognitive status groups (Alzheimer's disease, mild cognitive impairment, and healthy...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) provides $705,385 to Northeastern University to conduct a large-scale study investigating mediators and moderators of executive function training in older adults. The study aims to improve the rigor and reproducibility of research on cognitive plasticity in older adults, many of whom are at risk for Alzheimer's disease and related dementias. The study will collect data from 1,250 older adults aged 60+ to...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $300,892 project grant to Duke University to conduct research on high-resolution diffusion imaging of brain connectivity in healthy aging and Alzheimer's disease. The project aims to examine how white matter disconnection affects brain function in both healthy aging and Alzheimer's disease, leveraging a high-resolution multi-shot diffusion-weighted imaging (DWI) protocol. The research...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $1,249,957 Project Grant under CFDA 93.866 (Aging Research) to Advantage Therapeutics, Inc. in Florida. The grant aims to perform IND-enabling studies on a small molecule that is disease-modifying, low-cost, and has a long safety record for the treatment of Alzheimer's disease. The proposed molecule is designed to reduce brain inflammation and restore phagocytosis, thereby improving the...
- This $287,118 Project Grant was awarded on September 1, 2023 by the National Institute on Aging (NIA) under the Aging Research (CFDA 93.866) grant program. The grant will fund the development of techniques to use deep transfer learning and multimodal data, including brain MRIs, genetic information, and cognitive tests, to enable the early detection and forecasting of Alzheimer's disease progression. The University of Massachusetts (UMass), as the prime awardee, will create an end-to-end...
The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a 5-year, $210,168 project grant to the Medical University of South Carolina to support Dr. Stephanie Aghamoosa's research on developing non-pharmacological interventions for secondary prevention of dementia. The project aims to combine brain stimulation and computerized cognitive training to improve cognition in individuals with mild cognitive impairment (MCI). The research activities will help Dr. Aghamoosa, a clinical neuropsychologist, to become an expert in non-pharmacological interventions for MCI/Alzheimer's disease, obtain advanced training in clinical trial methodology, and establish herself as an independent NIH-funded investigator. The project aligns with NIA's strategic goal of identifying interventions to delay the progression of cognitive decline.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $210.2k | 8/28/25 |