Project Grant K23AA032563
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) program, is for a $735,930 feasibility and acceptability study of a large language model-based conversational agent for brief alcohol intervention among emerging adults (ages 18-29). The award will support the development, validation, and open trial of a conversational agent-delivered brief intervention designed to reduce alcohol use and problems...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $498,002 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the University of Illinois to conduct a study aimed at increasing alcohol abstinence in young adults with alcohol use disorder (AUD). The overall goals of this 3-year project are to: (1) test the efficacy of combining contingency management (CM) with problem-solving therapy (CM-PST) versus CM alone in a 2-arm pilot randomized controlled trial, and...
- This federal Project Grant award of $423,313, provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), aims to develop an AI-driven platform for identifying potential therapeutic candidates for Alcohol Use Disorder (AUD). The award to Biosymetrics Inc., based in Huntington, NY, will leverage the company's existing AI-based zebrafish behavioral screening technology and AUD-specific experimental findings to create a commercial...
- This Project Grant award, totaling $755,539, was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273). The funding will support research conducted by Emory University to evaluate the real-world utilization, effectiveness, and safety of glucagon-like peptide-1 receptor agonists (GLP-1RAs) as a treatment for alcohol use disorder (AUD). The project aims to leverage administrative claims data and linked electronic health records...
- This Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $306,528 to Addinex Technologies, Inc. to adapt their existing medication management system for use in decentralized clinical trials for substance use disorder (SUD). The primary goal is to develop a system that allows for at-home dispensing of medication, with features such as smartphone app-controlled dispensers using one-time passcodes,...
- This $673,500 Project Grant from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism will fund Amygdala Neurosciences, Inc. to develop new, potent, selective, and reversible inhibitors of aldehyde dehydrogenase 2 (ALDH2) for the treatment of alcohol use disorder. The goal is to implement an innovative screening technology to discover novel compounds that reduce craving and alcohol consumption by selectively inhibiting ALDH2 in a reversible manner, avoiding...
- This Project Grant award of $685,691 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), awarded under the Alcohol Research Programs (CFDA 93.273) on September 25, 2025, supports the development and piloting of an innovative Motivational Interviewing Video Reinforcement (MIVR) intervention. The MIVR approach aims to extend the impact of a single Motivational Interviewing session for patients with Alcohol-Associated Liver Disease (ALD) by providing personalized video clips of the...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), awarded a $999,393 Cooperative Agreement to Stress Therapeutics, Inc., a California-based pharmaceutical company, to conduct Investigational New Drug (IND)-enabling studies for a novel therapeutic to treat Alcohol Use Disorder (AUD). The key products and services to be delivered include: 1) Manufacture and validation of the test article for IND-enabling studies; 2) Development and...
- This Project Grant award was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), which falls under the federal Alcohol Research Programs (CFDA 93.273). The $692,723 award will support a double-blind, placebo-controlled clinical trial to test whether the drug suvorexant can be used as a novel therapeutic for alcohol use disorder (AUD) and stress-related drinking. The 5-year project, running from September 2025 through August 2030, will be conducted by researchers at The...
- This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under CFDA 93.273 - Alcohol Research Programs provides funding of $1,651,213.00 to Beam Diagnostics Inc. to develop and obtain FDA approval for Beacon-AUD, a digital diagnostic medical device for alcohol use disorder (AUD). The key objectives of this 3-year award include: 1) Conducting a multi-site clinical study on Beacon-AUD following FDA feedback, 2) Developing consensus on AUD treatment...
This federal Project Grant award of $194,062, provided by the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs), supports the development and pilot testing of a digital pill system (DPS) to measure and improve adherence to acamprosate medication in individuals with alcohol-associated liver disease (ALD) and alcohol use disorder (AUD). The key products/services to be delivered under this 5-year grant include: 1) Developing a user-centered adherence intervention paired with the DPS, called "AcamproSync", to personalize adherence support for participants with ALD and AUD taking acamprosate; 2) Conducting a pilot randomized controlled trial with 50 participants to assess the feasibility and acceptability of AcamproSync compared to standard treatment; and 3) Evaluating user experience and barriers to implementation of AcamproSync using the RE-AIM framework. This project aims to address gaps in medication adherence for this high-risk population and provide foundational data for scalable digital health interventions to improve adherence across various health conditions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $194.1k | 9/16/25 |