This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will provide $102,168 to support a research study conducted by the University of California, San Francisco (UCSF). The study aims to evaluate the effects of state-level initiatives to reduce early-term elective deliveries (EEDS) on maternal and newborn outcomes, as well as disparities in these outcomes. The...
This federal Project Grant award of $363,663 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to evaluate the impact of the Dobbs v. Jackson Supreme Court decision, which eliminated federal protections for abortion rights, on fertility, maternal health, and infant health outcomes over time and across different population subgroups. The research will use high-quality...
This federal Project Grant award of $747,911 from the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 (Child Health and Human Development Extramural Research program) is funding a hybrid implementation-effectiveness trial called "RI-SPHERES" at Women & Infants Hospital of Rhode Island. The RI-SPHERES program aims to reduce short- and long-term morbidity associated with hypertensive disorders of pregnancy (HDP) by expanding a technology-based...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to utilize the Desirability of Outcome Ranking (DOOR) methodology to generate and disseminate clearer interpretations of clinical trial results from two major NICHD-funded studies - the Maternal Fetal Medicine Units (MFMU) Network and the Management of Myelomeningocele Study...
This $1,918,854 Project Grant awarded by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 Child Health and Human Development Extramural Research program supports a multi-site, stepped-wedge randomized rollout trial to study the implementation and effectiveness of a Cesarean section risk calculator in diverse labor units across the United States. The study aims to evaluate the calculator's impact on reducing Cesarean delivery rates and maternal morbidity,...
This federal Project Grant award of $684,290 from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) supports a research project by Weill Medical College of Cornell University to develop risk models for predicting severe maternal morbidity (SMM) using multimodal clinical and social determinants of health (SDOH) data. The key objectives are to: 1) link longitudinal electronic health records and claims data to...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), funds the development and validation of a machine learning-based fetal monitoring system to predict and prevent fetal hypoxia. The $261,310 award will support the creation of a high-sensitivity, high-specificity predictive model using a multi-site dataset of 50,000 fetal monitoring tracings coupled with...
The National Institute of Child Health and Human Development (NICHD) awarded a $429,000 Project Grant (CFDA 93.865: Child Health and Human Development Extramural Research) to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, to develop a new imaging tool to assess placental hemodynamics during pregnancy. The study aims to determine if Subharmonic Aided Pressure Estimation (SHAPE) using contrast-enhanced ultrasound can provide a safe, non-invasive, and real-time method...
This $1,538,070.00 federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), will support research to investigate the role of mitochondrial nutrient transport in regulating trophoblast differentiation. The project aims to use CRISPR-Cas9 genetic tools to manipulate the expression of the mitochondrial pyruvate carrier (MPC) and glutamine transporter (SLC1A5VAR) in...
This Project Grant award, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the role of gestational hypoxia (a characteristic of gestational sleep apnea) in maternal brain health. The $117,226 award, with a project period from March 1, 2025 to February 28, 2027, will be used by the University of North Texas Health Science Center at Fort Worth...