Project Grant K01OD040624
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) awarded $116,005 to the University of Wisconsin-Madison on May 1, 2026, for a two-year project examining molecular mechanisms of neutrophil reverse migration in wound healing. The research deliverables include identification and characterization of distinct neutrophil subpopulations involved in reverse migration, tracking of their...
- Federal Grant Award Summary The University of Wisconsin–Madison received a $427,625 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), effective September 1, 2025, through August 31, 2027. The project develops and refines photoacoustic imaging (PAI) technology to quantitatively assess cutaneous wound healing by measuring biomarkers of...
- Federal Project Grant Award Summary The University of Wisconsin–Madison received a $124,929 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded July 1, 2026, with completion targeted for June 30, 2028. This award funds investigator-initiated basic biomedical research examining how epithelial tissue architecture regulates leukocyte migration strategies in vivo. The project employs...
- Federal Project Grant Award Summary The University of Wisconsin–Madison received a $1.59 million project grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 1, 2026, with completion expected June 30, 2030. This biomedical research grant funds a four-year investigation into the role of cyclic di-adenosine monophosphate (c-di-AMP) in Listeria monocytogenes pathogenesis. The project...
- Federal Grant Award Summary The University of Wisconsin – Madison received a $500,000 project grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), awarded August 1, 2025, with performance through July 31, 2027. The project delivers research and development services focused on developing and testing a novel immune inhibitory transgene for delivery to vascular composite allografts during normothermic preservation. The primary objective...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded the University of Wisconsin–Madison a Project Grant of $753,899 on February 2, 2026, with a completion date of January 31, 2031. This research grant funds a five-year investigation into the mechanisms by which butyrate—a microbiome-derived metabolite influenced by dietary fiber intake—affects Clostridioides difficile (CD)...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Wisconsin–Madison a $427,625 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2027. The award supports research and development activities focused on creating an innovative probiotic-based therapeutic delivery system. The project centers on developing plasmid-independent, carbohydrate-regulated...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a Project Grant of $392,918 to the University of Wisconsin-Madison under the Oral Diseases and Disorders Research program (CFDA 93.121) on August 1, 2025, for a two-year project period concluding July 31, 2027. The research project focuses on developing microphysiological systems (MPS) to model Sjögren's disease (SjD) salivary gland pathogenesis. The primary deliverable is the creation of...
- Federal Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), awarded University of Wisconsin-Madison a $553,640 Project Grant effective June 1, 2026, through April 30, 2031. This research project investigates the role of JMJD3 (a histone demethylase enzyme) as a molecular transducer that enables muscle stem cells to integrate environmental signals and...
- Federal Grant Award Summary The National Institutes of Health Office of the Director awarded University of Wisconsin–Madison a $1.49 million Project Grant under the Trans-NIH Research Support program (CFDA 93.310) on September 16, 2025, with a completion date of August 31, 2027. This research initiative focuses on developing and characterizing humanized mouse models to study Down syndrome immune responses, specifically addressing the immune dysregulation associated with trisomy 21. The project...
The National Institutes of Health Office of Research Infrastructure Programs (CFDA 93.351) awarded University of Wisconsin-Madison $130,383 on July 15, 2026, to support research on lymphatic regulation of neutrophil phenotypes in wound healing through advanced microphysiological systems (MPS). The project, which runs through June 30, 2030, develops and utilizes an in vitro wound microenvironment model using LumenExt technology with primary human cells to investigate immune-lymphatic-microbial dynamics. The research aims to deepen understanding of early wound healing mechanisms and explore microbiome-based therapeutic strategies to control infection, with particular focus on addressing antibiotic-resistant pathogens such as Staphylococcus aureus and reducing reliance on animal models for biomedical research. This Project Grant funds the development and application of a physiologically relevant microphysiological system that serves as a research resource and model for studying interactions between the lymphatic system, neutrophil immune responses, and skin microbiota during wound healing. The platform represents an advancement in research infrastructure by providing a human-relevant alternative to traditional animal models while generating insights into mechanisms that could inform therapeutic approaches to infection control and wound repair in clinical settings.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $130.4k | 7/7/26 |