This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $830,409 to Brigham & Women's Hospital Inc. to develop novel software and computational techniques that integrate real-time navigated electric-field mapping and source-space electroencephalogram (EEG) analysis during transcranial magnetic stimulation (TMS) to improve the accuracy of targeting and dosimetry for individualized TMS treatment. The...
This Project Grant award of $781,464 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund research to develop a multidimensional atlas of causal brain circuitry. The project aims to use brain stimulation and neuroimaging techniques to map the causal relationships between specific brain regions and a range of behaviors relevant to mental illness, including transdiagnostic symptoms and diagnosis-specific symptoms. The...
The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), was awarded a $459,250 federal Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The 2-year grant, running from August 15, 2023 to August 14, 2025, will fund research to investigate the state-dependent effects of transcranial alternating current stimulation (TACS) on theta-gamma cross-frequency coupling and fronto-parietal...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $2,621,650.00 to The General Hospital Corporation (Massachusetts General Hospital) to conduct a multi-site clinical trial evaluating the use of a transcranial magnetic stimulation-electroencephalography (TMS-EEG) device for detecting and predicting recovery of consciousness...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $156,656 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to conduct advanced functional MRI (fMRI) studies of cerebral cortical layers in the human brain. The research aims to validate the use of "linescan fMRI," a high-resolution technique that can map brain activity across individual...
The National Institute of Mental Health (NIMH) awarded a $600,000 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to support the purchase of a next-generation 3 Tesla human MRI scanner for mental health research at the Athinoula A. Martinos Center for Biomedical Imaging. This new high-performance MRI system will replace an outdated 16+-year-old scanner and enable...
This federal Project Grant award of $831,180 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support the "PSYCHEMERGE: ADVANCING PRECISION PSYCHIATRY" research project led by The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The key products and services to be delivered through this 5-year grant, which begins on September 1, 2024, include: Developing a nationwide federated...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $2,359,174 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct research on the biophysical mechanisms of cortical microstimulation. The project aims to develop a more mechanistic understanding of how direct local electrical stimulation...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), aims to advance transcranial magnetic stimulation (TMS) technologies for psychiatric disorders. The $420,468 award to the Regents of the University of Minnesota will fund research to validate a closed-loop approach where real-time electroencephalographic (EEG) recordings inform the timing of TMS at the prefrontal cortex. The research will identify markers...
This National Institute of Mental Health (NIMH) Project Grant award under the Mental Health Research Grants program (CFDA 93.242) provides $107,948.00 to The Trustees of the University of Pennsylvania to conduct research aimed at elucidating the glutamatergic mechanisms by which repetitive transcranial magnetic stimulation (rTMS) may treat major depressive disorder (MDD). The project will leverage ultra-high field (7T) neuroimaging techniques, including glutamate chemical exchange saturation...