Project Grant K01HL188804
Award Date 9/1/26
Completion Date 8/31/31
Dollars Obligated $132K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Houston, TX 77030, USA
Similar Awards
- The National Heart, Lung, and Blood Institute awarded Baylor College of Medicine $625,035 on August 17, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to support research into the molecular mechanisms of mitochondrial calcium exchange in the heart. The research addresses mitochondrial calcium overload, which triggers cell death and tissue damage during ischemia-reperfusion injury—a secondary phase of cardiac damage that can account for up to 50 percent of final infarct...
- Federal Grant Award Summary Boston Children's Hospital received a $279,644 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 1, 2025, with completion scheduled for August 31, 2027. The grant funds research to develop and validate time to return of spontaneous circulation (ROSC) as a novel primary outcome measure for pediatric in-hospital cardiac arrest (P-IHCA) clinical trials. The research...
- The National Heart, Lung, and Blood Institute awarded Baylor College of Medicine $701,116 under the Cardiovascular Diseases Research program (CFDA 93.837) on September 1, 2026, to investigate transcriptional mutagenesis as a novel mechanism driving heart failure. The research examines how oxidative stress promotes formation of 8-oxo-deoxyguanosine lesions in DNA, which disrupts transcriptional fidelity in cardiomyocytes. Aim 1 integrates long-read single-nucleus RNA sequencing from human heart...
- The National Heart, Lung, and Blood Institute awarded Baylor College of Medicine $1,199,830 on September 16, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop machine learning algorithms and clinical decision support tools for early detection and dynamic prediction of acute kidney injury following cardiac surgery. The project, titled "Leveraging Machine Learning for Dynamic Prediction and Mitigation of Acute Kidney Injury After Cardiac Surgery,"...
- The National Heart, Lung, and Blood Institute awarded The Children's Hospital Corporation, doing business as Boston Children's Hospital, $857,878 for a Project Grant (R01HL188153) on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837). The award funds development and evaluation of pediatric cardiac foundation models—machine learning models pre-trained on large volumes of unlabeled electrocardiogram (ECG), echocardiogram (ECHO), chest X-ray, and clinical text...
- The National Heart, Lung, and Blood Institute awarded Baylor College of Medicine $670,574 under the Cardiovascular Diseases Research program (CFDA 93.837) on August 15, 2026, to conduct research on diurnal adipose-heart lipid dynamics in the obesity paradox of heart failure. The research investigates why patients with higher body mass index experiencing heart failure exhibit better prognosis than those with lower BMI, despite obesity being a heart failure risk factor. The project tests the...
- The National Heart, Lung, and Blood Institute awarded Baylor College of Medicine $643,349 under the Cardiovascular Diseases Research program (CFDA 93.837) on August 17, 2026, to investigate the role of gasdermin D (GSDMD) inhibition in reducing inflammation-related atrial fibrillation risk associated with clonal hematopoiesis and aging. The research employs bone marrow transplantation, deep cardiac phenotyping, single-cell transcriptomics, and genetic analyses to elucidate how clonal...
- The National Heart, Lung, and Blood Institute awarded Baylor University $562,494 under the Cardiovascular Diseases Research program (CFDA 93.837) on August 15, 2026 for a Project Grant (R15HL179650) to identify metabolic drivers of cancer cachexia-associated cardiomyopathy. The research will use pre-clinical cancer cachexia mouse models to identify the role of mitochondrial dysfunction on metabolism and mechanical function in hearts and cardiac muscle cells from mice with cancer cachexia. Mice...
- The National Heart, Lung, and Blood Institute awarded Children's Research Institute $1,818,088 on July 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate how postnatal hypoxemia—reduced blood oxygen levels present in cyanotic congenital heart disease—impacts cardiac maturation and surgical recovery outcomes in pediatric patients. The project will examine the interaction between hypoxemia, myocardial immaturity, and postoperative complications through...
- The National Heart Lung and Blood Institute awarded The University of Texas Southwestern Medical Center $1.371 million on September 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct a multi-center observational study of the association between ventilation and cardiac arrest outcome. The study measures ventilation during cardiopulmonary resuscitation using thoracic bioimpedance (electrical resistance) monitored through defibrillator pads. The recipient has...