This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $594,547.00 to Harvard Medical School to conduct research on the regulation of arousal and sleep quality through gut-to-brain signaling. The project aims to characterize the molecular mechanisms by which dietary proteins are sensed in the gut and how this information is conveyed to the brain to modulate sensory responsiveness and sleep depth, without affecting overall sleep duration. The research will investigate the impact of this gut-brain pathway on health and longevity across the lifespan. As a Child award, this project likely involves collaboration with the parent organization, Harvard College President & Fellows Of, which has a history of participating in federal grant sub-awards for various research initiatives in fields such as medicine, engineering, and social sciences.
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