This Project Grant award of $602,358, provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), aims to assess the contribution of epigenetics to cardiovascular risk in African American women. The project will identify epigenetic biomarkers of cardiovascular disease and its environmental determinants, and evaluate if these biomarkers can contribute to risk prediction assessments. The research will be conducted by the...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $498,991.40 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of Arkansas. The grant, effective January 2, 2025 through December 31, 2027, will support the development of microphysiological systems to investigate molecular pathways and cardiomyocyte function in response to hypoxic cardiac injury associated with myocardial infarction and ischemia-reperfusion injury. The project aims to...
This Project Grant award of $540,771 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop a personalized, socially conscious stroke risk stratification tool for patients with atrial fibrillation (AF). The key objectives are to: 1) Discover new clinical and socioeconomic risk factors for stroke in AF patients by leveraging large datasets including social determinants of health (SDOH) data; 2) Build novel,...
This Project Grant award, funded by the National Heart, Lung, and Blood Institute (NHLBI) under CFDA 93.837 - Cardiovascular Diseases Research, provides $815,229 to The University of Texas Southwestern Medical Center to conduct advanced research on cardiovascular disease susceptibility and resilience in Black Americans. The key objectives are to: 1) Identify proteins and protein networks associated with clinical and subclinical cardiac dysfunction, 2) Pinpoint proteins and networks linked to...
The University of Arkansas for Medical Sciences (UAMS) has been awarded a $631,253 Project Grant by the National Institute on Minority Health and Health Disparities (NIMHD) under the Minority Health and Health Disparities Research program (CFDA 93.307). The grant aims to identify employment disparities among Black breast cancer survivors living in the rural South, determine the relationships between physical activity and work outcomes, and understand the role of factors like fatigue,...
This Project Grant awarded by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $147,486 to Baylor College of Medicine to conduct research aimed at improving genetic testing for cardiovascular disease (CVD). The key objectives are to: Study the genetics of CVD and lipoprotein(a) (Lp(a)) across diverse and mixed-ancestry populations using novel tools that appropriately evaluate ancestry. This includes evaluating the role of linkage...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under CFDA 93.837 Cardiovascular Diseases Research will support a $224,142 epidemiologic study to determine the prevalence and correlates of atherosclerotic resilience, measured by the absence of coronary artery calcium (CAC=0), among 4,000 participants in the Risk Underlying Rural Areas Longitudinal (RURAL) cohort study across the southeastern U.S. The research aims to provide insights into the biopsychosocial...
This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $642,454.00 to The Ohio State University to develop an artificial intelligence-based system for predicting the risk of cardiotoxicity in breast cancer patients undergoing anti-tumor therapies. The project aims to complement electronic health record data with multimodal data collected through wearable sensors and a conversational chatbot to create an improved risk prediction model....
This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) to the H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc. will support a $734,942 research project over 5 years from August 2025 to July 2030. The research aims to evaluate how biological aging metrics, such as epigenetic clocks and leukocyte composition, are associated with cardiovascular disease (CVD) and mortality risk in breast cancer survivors. The project will...
This $140,329 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will support research evaluating racial and ethnic disparities in patient outcomes and intra-arrest resuscitation practices for in-hospital cardiac arrest (IHCA). The key objectives are to: 1) Examine racial and ethnic disparities in time to return of spontaneous circulation (ROSC), survival to hospital discharge, and favorable functional...