The University of Utah has been awarded a $769,998 federal Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant, effective September 5, 2023, supports a project titled "Personalized Risk Stratification in Atrial Fibrillation Using Portable, Explainable Artificial Intelligence." The objectives are to discover new risk factors for stroke in patients with atrial fibrillation, including social...
This is a Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research Federal Grant Program (CFDA 93.837). The $1,527,766 award, which began on September 9, 2024 and will run through May 31, 2029, aims to develop, validate, and demonstrate the impact of a novel in-hospital mortality prediction model (MPM) that optimizes fairness across subgroups defined by race, ethnicity, sex, age, language, insurance status, and social...
The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research Federal Grant Program (CFDA 93.837), awarded a $299,604 Project Grant to Case Western Reserve University (CWRU) to develop and validate a novel "transfer volume regression" machine learning model for predicting major cardiovascular events, including stroke, heart attack, heart failure, and death. The 4-year project, starting September 1, 2024, aims to create a standardized, fairness-aware,...
This Project Grant award, in the amount of $2,096,284.00, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research Federal Grant Program (CFDA 93.837). The purpose of the project is to evaluate the utilization and outcomes of left atrial appendage occlusion (LAAO) procedures compared to therapeutic alternatives in older adults with atrial fibrillation and frailty. The research will leverage multiple real-world data sources and advanced...
This $165,364 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to identify novel contextual and genomic blood pressure measures to enhance cardiovascular disease prediction and management among young adults aged 18 to 39 years. The key objectives are to: Identify novel ambulatory blood pressure patterns capturing dynamic responses to everyday factors using machine learning approaches. Derive a...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), will fund a 1-week daily diary study to examine the influence of intersectional anticipated and vicarious stigma on home blood pressure among a diverse sample of 400 adults. The $2,709,341.45 award, spanning from September 1, 2024 to March 21, 2025, will support the recruitment and data collection efforts, including twice-daily...
This federal Project Grant award of $179,280 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to address disparities in polygenic risk scores (PRS) for coronary heart disease (CHD) across diverse populations. The principal investigator, Dr. Tcheandjieu, will analyze genetic data from over 2.1 million individuals of European, African, Indigenous American, and Asian ancestries to explore population-specific differences...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), aims to develop novel polygenic score methods to predict medication response for African American patients with common chronic conditions. The $246,776 award, with a performance period from August 2024 to July 2026, will fund a collaborative research partnership between Henry Ford Health and Michigan State University Health Sciences. The key...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $769,761 to Weill Medical College of Cornell University to support research on the mechanisms of obesity-induced atrial fibrillation (AF). The research aims to: 1) Dissect the role of the nicotinamide adenine dinucleotide (NAD+) pathway in obesity-induced AF, and 2) Assess the role of the ATF6 endoplasmic reticulum stress...
The University of Miami received a $3,596,019 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research federal grant program (CFDA 93.837). The grant, titled "Cardiac Imaging of Neuro-Embolic Mechanisms in Atriopathies Causing Stroke (CINEMAS)", will fund a 5-year research study to identify clinical and mechanistic characteristics of left atrial appendage (LAA) stasis using 4D flow MRI to improve strategies for preventing...