Project Grant K01DK147576
- Federal Grant Award Summary The University of Utah received a $729,085 Project Grant awarded September 1, 2025, through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds basic biomedical research investigating the mechanisms of mitochondria-driven hepatocyte injury, with a project completion date of June 30, 2030. The research focuses on the EFHD1 (EF-Hand...
- Federal Grant Award Summary The University of Utah received a $1,573,594 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective July 1, 2025 through June 30, 2030. The award funds a hybrid effectiveness-implementation cluster randomized controlled trial to scale the Building Healthy Families (BHF) program—an evidence-based childhood obesity intervention...
- Federal Grant Award Summary The University of Florida received a $795,806 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective May 20, 2026 through April 30, 2031. The research project, titled "Molecular Mechanisms of Stress Hormone Control of Skeletal Muscle Metabolism," will be conducted at the University of Florida's Jupiter,...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded $1.58 million to the University of Kansas Medical Center Research Institute, Inc. under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct a comprehensive clinical research study examining changes in body composition, particularly muscle mass, among adults with obesity receiving contemporary anti-obesity medications. The study,...
- Federal Project Grant Award Summary The University of Massachusetts Medical School received a $2.64 million Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 1, 2025, through August 31, 2029. This award funds biomedical research investigating novel mitochondrial mechanisms underlying obesity pathogenesis, with specific focus on...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $1.26 million Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct fundamental biomedical research on the regulation of ghrelin secretion by the sympathetic nervous system (SNS). Awarded on August 1, 2025, with a completion date of March 31, 2030, this...
- Federal Grant Award Summary The University of Utah received a $654,530 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 1, 2025 through July 31, 2029. This research project investigates the role of serum glucocorticoid kinase 1 (SGK1) in cardiometabolic heart failure with preserved ejection fraction (HFPEF), addressing a critical unmet medical need affecting approximately 33 million...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The University of Texas Health Science Center at San Antonio a $707,781 Project Grant on May 22, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds biomedical research through March 31, 2031, focused on identifying cell type-specific and insulin-responsive quantitative trait loci (QTLs) in human skeletal muscle...
- Federal Project Grant Award Summary Tufts University School of Medicine received a $735,358 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award was obligated on May 21, 2026, with a completion date of February 28, 2030. The research focuses on enteroendocrine cell reprogramming as a novel therapeutic approach to address chronic obesity and...
- Federal Project Grant Award Summary The University of Utah's Office of Sponsored Projects received a $635,681 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded on June 20, 2026, with completion targeted for February 28, 2030. This award supports investigator-initiated research examining the pyruvate-lactate metabolic axis in heart failure and cardiac recovery. The research project will quantify...
The University of Utah's Office of Sponsored Projects received a $143,550 Project Grant award (CFDA 93.847: Diabetes, Digestive, and Kidney Diseases Extramural Research) from the National Institute of Diabetes and Digestive and Kidney Diseases, effective July 1, 2026 through February 28, 2031. This award funds investigator-initiated research examining skeletal muscle mitochondrial efficiency in the context of glucagon-like peptide-1 receptor agonist (GLP-1RA)-induced weight loss, with primary focus on how semaglutide affects mitochondrial oxidative phosphorylation efficiency—defined as adenosine triphosphate (ATP) production per oxygen consumed—in skeletal muscle tissue. The funded research will deliver integrated physiological, biochemical, and metabolic analyses designed to elucidate the cellular mechanisms linking pharmacologically induced weight loss to improved skeletal muscle energetics. Key deliverables include assessment of whether enhanced mitochondrial efficiency scales with weight loss, persists following treatment cessation, and contributes to increased physical activity and sustained glycemic control in individuals with obesity. Findings from this project are intended to inform future clinical strategies for sustaining the metabolic benefits of weight loss in obese populations and to advance understanding of how skeletal muscle energetics mediate the systemic effects of weight loss intervention.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $143.6k | 6/19/26 |