Project Grant K01DK146239
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Washington University $537,032 on July 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to support research on palmitoylation and type 2 diabetes through March 31, 2031. The project investigates the role of protein S-palmitoylation in beta cell dysfunction underlying type 2 diabetes. The research focuses on acyl-protein thioesterase 1 (APT1), an enzyme that...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Washington University $277,506 on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), a K01 Mentored Career Development Award supporting research into cytoskeletal regulation of gut tube organogenesis and maturation of stem cell-derived islets. The award funds a career development training plan designed to transition the candidate to an independent...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Washington University $720,353 on March 25, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Assistance Listing Project Grant R01DK141555). The award funds research to identify and elucidate the functioning of hypothalamic neural circuits that regulate energy balance and metabolism, with focus on obesity-associated metabolic diseases. The research targets a...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Washington University $578,846 on February 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate brown adipose tissue–derived nidogen-2 as a potential diabetes therapeutic. The research addresses hyperglycemia and hypoglycemia risks in type 1 and advanced type 2 diabetes. Preliminary data show that nidogen-2, a secreted protein isolated from brown...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Arkansas for Medical Sciences $717,457 on February 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate metabolic rewiring of T cells and the pathogenic connection between diabetes and hypertension. The research examines immune-metabolic crosstalk in the progression from type 2 diabetes to hypertension using a high-fat diet-induced...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Washington University a Project Grant totaling $233,250 on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports research into the role of protein phosphatase 1K (PPM1K) in macrophage activation and metabolic disease. The research addresses a critical knowledge gap regarding branched chain amino...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Washington University $764,322 on August 10, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Project Grant R01DK144511). The award funds development of induced pluripotent stem cell (iPSC) modeling platforms to investigate partial lipodystrophy syndromes, a group of rare disorders characterized by regional loss of white adipose tissue that leads to insulin...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Massachusetts General Hospital $251,626 on April 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct basic research on c-kit receptor signaling in kidney collecting duct function. The research investigates the role of c-kit receptor signaling in modulating collecting duct epithelial cell composition and function. The project uses c-kit "sash" mice...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Illinois $160,575 on July 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Project Grant K01DK147658). The award funds a three-year study of Medicaid alternative payment model (APM) implementation and evidence-based practice adoption in federally qualified health centers (FQHCs) to improve diabetes outcomes. The research addresses how FQHCs, which...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Washington University a Project Grant totaling $1,491,303 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for the period September 5, 2025, through September 4, 2029. This award supports basic biomedical research investigating the molecular mechanisms that drive progression from acute kidney injury (AKI) to chronic kidney...
The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Washington University $158,554 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research investigating the role of ATP-sensitive potassium (KATP) channels in type 2 diabetes mellitus development. The project will examine mouse models of type 2 diabetes and human diabetic subjects to probe potential alterations in KATP channel activity and understand their relevance to disease progression and management. The research addresses a paradoxical pattern observed in both animal and human systems: initial hypersecretion of insulin followed by secretory failure, potentially reflecting progression similar to that seen in KATP-dependent hyperinsulinism. Performance occurs in St. Louis, Missouri, with work concluding on May 31, 2030. The award is classified as a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $158.6k | 8/26/26 |