Project Grant K01DA061975
- The federal Project Grant award with ID DP2DA062283 was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The $2,542,500 grant, awarded on September 1, 2024, will support the development of novel econometric methods and a unified framework for integrating real-world evidence (RWE) to analyze inconclusive randomized controlled trials (RCTs) focused on opioid use disorder (OUD) treatments. The project, to be conducted by Weill...
- This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is intended to develop and evaluate an adaptive psychological intervention to improve pain management and reduce opioid use following an injury. The $264,995 grant, awarded on September 15, 2025, will fund the optimization and feasibility testing of a two-part intervention. The first part is a 15-minute computerized brief intervention focused on...
- This federal Project Grant award of $144,252 from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) will fund a research program led by Dr. Carreiro at the University of Massachusetts Medical School (UMMS). The key objectives are to: Develop a novel wearable sensing system called "MINDER" to continuously monitor physiological parameters and use machine learning to accurately identify adherence to buprenorphine treatment for opioid use...
- This federal Project Grant award of $798,828.00 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to discover novel small molecule therapeutics for the safe and effective treatment of opioid use disorder (OUD). The key products and services to be delivered include: The development of an AI platform called M3.AI that will integrate target-based and phenotype-based methodologies to efficiently identify new drug candidates for OUD...
- The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $1,445,752 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to New York University School of Medicine. The grant, titled "Characterizing Complex OUD Care Trajectories and Outcomes Following Acute Service Utilization: A Population-Based Data Linkage Study," aims to apply novel research approaches to better understand real-world opioid use disorder (OUD)...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support a study to characterize treatment utilization and identify predictors of treatment engagement during the critical community re-entry period for adults with opioid use disorder (OUD) who have completed residential OUD treatment. The $147,486 award, with a performance period from December 20, 2024 to August 31, 2026, will leverage innovative...
- This federal Project Grant award for $188,995.00 was provided by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports research at the University of Pittsburgh focused on understanding, preventing, and treating substance use disorders. The project aims to develop novel interventions, explore neuroscientific mechanisms of addiction, and improve treatment strategies. The...
- This federal Project Grant award, with ID K01DA060359, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The $195,728 grant will fund a 5-year study to assess the acceptability and feasibility of using pharmacogenomic (PGX) testing to guide opioid use disorder (OUD) treatment. The key objectives of this project are to: 1) identify barriers and facilitators impacting the acceptability and feasibility of a PGX testing...
- This federal Project Grant award of $767,506 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to leverage integrative modeling and AI-based tools to develop safer opioid painkillers. The project focuses on understanding how low-efficacy opioid receptor (MOR) agonists activate MOR-mediated G protein pathways differently from high-efficacy opioid drugs, in order to inform the design of safer opioid therapeutics. The award...
- This Project Grant award of $398,137 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is for developing high-precision epigenetic therapeutics to address the growing opioid use disorder (OUD) epidemic in the United States. The award will enable Boston Interactome LLC to apply a novel approach targeting protein-protein interactions of the neuronal G9A complex, a key regulator of DFosB expression under chronic opioid exposure....
This federal Project Grant award, titled "Dynamic Treatment Regimes for Personalized Opioid Use Disorder Care," was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The $199,800 award supports the research efforts of Dr. Jason Brian Gibbons, an Assistant Professor at the University of Colorado Anschutz Medical Campus, over a 5-year period from August 2025 to July 2030. The overarching objective of the project is to develop dynamic, personalized treatment recommendations for patients with opioid use disorders using machine learning-based dynamic treatment regime (DTR) methods. The research will leverage extensive health records from a national behavioral health provider, Discovery Behavioral Health, as well as linked claims and death data, to assess the relationship between patient characteristics and treatment responses over time. The findings will be used to craft optimal treatment decision rules to personalize and improve opioid use disorder care, with the goal of reducing overdose deaths.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $199.8k | 7/25/25 |